Biffl Walter L, Kaups Krista L, Pham Tam N, Rowell Susan E, Jurkovich Gregory J, Burlew Clay Cothren, Elterman J, Moore Ernest E
Department of Surgery, Denver Health Medical Center/University of Colorado, Denver, Colorado 80204-4507, USA.
J Trauma. 2011 Dec;71(6):1494-502. doi: 10.1097/TA.0b013e31823ba1de.
The optimal management of stable patients with anterior abdominal stab wounds (AASWs) remains a matter of debate. A recent Western Trauma Association (WTA) multicenter trial found that exclusion of peritoneal penetration by local wound exploration (LWE) allowed immediate discharge (D/C) of 41% of patients with AASWs. Performance of computed tomography (CT) scanning or diagnostic peritoneal lavage (DPL) did not improve the D/C rate; however, these tests led to nontherapeutic (NONTHER) laparotomy (LAP) in 24% and 31% of cases, respectively. An algorithm was proposed that included LWE, followed by either D/C or admission for serial clinical assessments, without further imaging or invasive testing. The purpose of this study was to evaluate the safety and efficacy of the algorithm in providing timely interventions for significant injuries.
A multicenter, institutional review board-approved study enrolled patients with AASWs. Management was guided by the WTA AASW algorithm. Data on the presentation, evaluation, and clinical course were recorded prospectively.
Two hundred twenty-two patients (94% men, age, 34.7 years ± 0.3 years) were enrolled. Sixty-two (28%) had immediate LAP, of which 87% were therapeutic (THER). Three (1%) died and the mean length of stay (LOS) was 6.9 days. One hundred sixty patients were stable and asymptomatic, and 81 of them (51%) were managed entirely per protocol. Twenty (25%) were D/C'ed from the emergency department after (-) LWE, and 11 (14%) were taken to the operating room (OR) for LAP when their clinical condition changed. Two (2%) of the protocol group underwent NONTHER LAP, and no patient experienced morbidity or mortality related to delay in treatment. Seventy-nine (49%) patients had deviations from protocol. There were 47 CT scans, 11 DPLs, and 9 laparoscopic explorations performed. In addition to the laparoscopic procedures, 38 (48%) patients were taken to the OR based on test results rather than a change in the patient's clinical condition; 17 (45%) of these patients had a NONTHER LAP. Eighteen (23%) patients were D/C'ed from the emergency department. The LOS was no different among patients who had immediate or delayed LAP. Mean LOS after NONTHER LAP was 3.6 days ± 0.8 days.
The WTA proposed algorithm is designed for cost-effectiveness. Serial clinical assessments can be performed without the added expense of CT, DPL, or laparoscopy. Patients requiring LAP generally manifest early in their course, and there does not appear to be any morbidity related to a delay to OR. These data validate this approach and should be confirmed in a larger number of patients to more convincingly evaluate the algorithm's safety and cost-effectiveness compared with other approaches.
对于稳定的腹部刺伤(AASW)患者,最佳治疗方案仍存在争议。西方创伤协会(WTA)最近的一项多中心试验发现,通过局部伤口探查(LWE)排除腹膜穿透可使41%的AASW患者立即出院(D/C)。计算机断层扫描(CT)或诊断性腹腔灌洗(DPL)并未提高出院率;然而,这些检查分别导致24%和31%的病例进行了非治疗性(NONTHER)剖腹手术(LAP)。提出了一种算法,包括LWE,然后是D/C或入院进行系列临床评估,无需进一步的影像学检查或侵入性检测。本研究的目的是评估该算法在为严重损伤提供及时干预方面的安全性和有效性。
一项经机构审查委员会批准的多中心研究纳入了AASW患者。治疗遵循WTA的AASW算法。前瞻性记录患者的临床表现、评估和临床病程数据。
共纳入222例患者(94%为男性,年龄34.7岁±0.3岁)。62例(28%)立即进行了LAP,其中87%为治疗性(THER)手术。3例(1%)死亡,平均住院时间(LOS)为6.9天。160例患者病情稳定且无症状,其中81例(51%)完全按照方案进行治疗。20例(25%)在LWE结果为阴性后从急诊科出院,11例(14%)在临床状况改变时被送往手术室(OR)进行LAP。方案组中有2例(2%)进行了NONTHER LAP,没有患者因治疗延迟而出现并发症或死亡。79例(49%)患者未按方案治疗。进行了47次CT扫描、11次DPL检查和9次腹腔镜探查。除了腹腔镜手术外,38例(48%)患者是根据检查结果而非患者临床状况的变化被送往OR的;其中17例(45%)患者进行了NONTHER LAP。18例(23%)患者从急诊科出院。立即或延迟进行LAP的患者之间LOS无差异。NONTHER LAP后的平均LOS为3.6天±0.8天。
WTA提出的算法旨在实现成本效益。可以进行系列临床评估,而无需增加CT、DPL或腹腔镜检查的费用。需要进行LAP的患者通常在病程早期就会表现出来,似乎没有因延迟手术而导致的任何并发症。这些数据验证了这种方法,应在更多患者中得到证实,以更令人信服地评估该算法与其他方法相比的安全性和成本效益。