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体重指数(BMI):一种针对高龄老人营养不良情况的简单、快速且具有临床意义的指标?

BMI: a simple, rapid and clinically meaningful index of under-nutrition in the oldest old?

作者信息

Miller Michelle D, Thomas Jolene M, Cameron Ian D, Chen Jian Sheng, Sambrook Philip N, March Lyn M, Cumming Robert G, Lord Stephen R

机构信息

Department of Nutrition and Dietetics, Flinders University, Adelaide, SA, Australia.

出版信息

Br J Nutr. 2009 May;101(9):1300-5. doi: 10.1017/s0007114508076289.

Abstract

BMI is commonly used as a sole indicator for the assessment of nutritional status. While it is a good predictor of morbidity and mortality among young and middle-aged adults, its predictive ability among the oldest old remains unclear. The objective of the present study was to investigate the relationship between BMI and risk of falls, fractures and all-cause mortality among older Australians in residential aged care facilities. One thousand eight hundred and forty-six residents of fifty-two nursing homes and thirty hostels in northern Sydney, Australia, participated in the present study. Baseline weight and height were measured and BMI (kg/m2) calculated. For 2 years following the baseline measurements, incidence and date of all falls and fractures were recorded by research nurses who visited the facilities regularly and date of death was documented based on the participants' records at each facility. Cox proportional hazards regression models were calculated to determine the relationship between baseline BMI and time to fall, fracture or death, within 2 years following the baseline measures taken to be the censoring date. After adjustments were made for age, sex and level of care, low BMI (,22 kg/m2) increased the risk of fracture by 38% (hazard ratio = 1.38, 95% CI 1.11, 1.73) and all-cause mortality by 52% (hazard ratio = 1.52, 95% CI 1.30, 1.79). The magnitude of this effect was only slightly reduced when adjustments were further made to incorporate cognition, number of medications, falls and fracture in the subsequent 2-year period. In conclusion, BMI has predictive ability in the area of fracture and all-cause mortality for residents of aged care facilities. It is a simple and rapid indicator of nutritional status rendering it a useful nutrition screen and goal for nutrition intervention.

摘要

体重指数(BMI)通常被用作评估营养状况的唯一指标。虽然它是年轻和中年成年人发病和死亡的良好预测指标,但其在高龄老年人中的预测能力仍不明确。本研究的目的是调查澳大利亚老年护理机构中老年人的BMI与跌倒、骨折风险及全因死亡率之间的关系。澳大利亚悉尼北部52家养老院和30家宿舍的1846名居民参与了本研究。测量了基线体重和身高,并计算了BMI(kg/m²)。在基线测量后的2年里,定期走访这些机构的研究护士记录了所有跌倒和骨折的发生率及日期,并根据各机构参与者的记录记录了死亡日期。计算Cox比例风险回归模型,以确定基线BMI与基线测量后2年内跌倒、骨折或死亡时间之间的关系,将基线测量时间作为截尾日期。在对年龄、性别和护理水平进行调整后,低BMI(<22 kg/m²)使骨折风险增加38%(风险比=1.38,95%置信区间1.11,1.73),全因死亡率增加52%(风险比=1.52,95%置信区间1.30,1.79)。当进一步调整以纳入随后2年期间的认知、用药数量、跌倒和骨折情况时,这种影响的程度仅略有降低。总之,BMI在老年护理机构居民的骨折和全因死亡率方面具有预测能力。它是营养状况的一个简单快速指标,使其成为一个有用的营养筛查工具和营养干预目标。

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