Lee Beom-Jae, Park Jong-Jae, Chun Hoon-Jai, Kim Ji-Hoon, Yeon Jong-Eun, Jeen Yoon-Tae, Kim Jae-Seon, Byun Kwan-Soo, Lee Sang-Woo, Choi Jae-Hyun, Kim Chang-Duck, Ryu Ho-Sang, Bak Young-Tae
Division of Gastroenterology, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Gurodong-gil 97, Guro-gu, Seoul 152-703, South Korea.
World J Gastroenterol. 2009 May 14;15(18):2265-9. doi: 10.3748/wjg.15.2265.
To evaluate the efficacy of cola treatment for gastric phytobezoars, including diospyrobezoars.
A total of 17 patients (range: 48 to 78 years) with symptomatic gastric phytobezoars treated with cola and adjuvant endoscopic therapy were reviewed. Three liters of cola lavage (10 cases) or drink (7 cases) were initially used, and then endoscopic fragmentation was done for the remnant bezoars by using a lithotripsy basket or a polypectomy snare. The overall success of dissolving a gastric phytobezoars with using three liters of cola and the clinical and endoscopic findings were compared retrospectively between four cases of complete dissolution by using only cola and 13 cases of partial dissolution with cola.
After 3 L of cola lavage or drinking, a complete dissolution of bezoars was achieved in four patients (23.5%), while 13 cases (76.5%) were only partially dissolved. Phytobezoars (4 of 6 cases) were observed more frequently than diospyrobezoars (0 of 11) in the group that underwent complete dissolution (P = 0.006). Gender, symptom duration, size of bezoar and method of cola administration were not significantly different between the two groups. Twelve of 13 patients with residual bezoars were completely treated with a combination of cola and endoscopic fragmentation.
The rate of complete dissolution with three liters of cola was 23.5%, but no case of diospyrobezoar was completely dissolved using this method. However, pretreatment with cola may be helpful and facilitate endoscopic fragmentation of gastric phytobezoars.
评估可乐治疗胃植物性胃石（包括柿子胃石）的疗效。
回顾性分析17例（年龄范围：48至78岁）有症状的胃植物性胃石患者，采用可乐及辅助内镜治疗。最初使用3升可乐灌洗（10例）或饮用（7例），然后使用碎石篮或息肉切除圈套器对残留胃石进行内镜下破碎。回顾性比较仅使用可乐完全溶解的4例与使用可乐部分溶解的13例胃植物性胃石患者，使用3升可乐溶解胃植物性胃石的总体成功率以及临床和内镜检查结果。
3升可乐灌洗或饮用后，4例患者（23.5%）胃石完全溶解，13例（76.5%）仅部分溶解。在完全溶解组中，植物性胃石（6例中的4例）比柿子胃石（11例中的0例）更常见（P = 0.006）。两组患者的性别、症状持续时间、胃石大小和可乐给药方法无显著差异。13例残留胃石患者中的12例通过可乐和内镜破碎联合治疗得到完全治愈。
3升可乐完全溶解胃石的比例为23.5%，但使用该方法无1例柿子胃石完全溶解。然而，可乐预处理可能有助于促进胃植物性胃石的内镜破碎。
