Department of Surgery and Integrated Clinic, Division of Periodontics, São Paulo State University (UNESP), Rua Jose Bonifácio 1193, Centro, 16050-300 Araçatuba, SP, Brasil.
Lasers Med Sci. 2010 Mar;25(2):197-206. doi: 10.1007/s10103-009-0678-z. Epub 2009 May 14.
The aim of this study was to compare low-level laser therapy (LLLT) as adjuvant treatment for induced periodontitis with scaling and root planing (SRP) in dexamethasone-treated rats. One-hundred twenty rats were divided into groups: D group (n = 60), treated with dexamethasone; ND group (n = 60) treated with saline solution. In both groups, periodontal disease was induced by ligature at the left first mandibular molar. After 7 days, the ligature was removed and all animals were subjected to SRP and were divided according to the following treatments: SRP, irrigation with saline solution (SS); SRP + LLLT, SS and laser irradiation (660 nm; 24 J; 0.428 W/cm(2)). Ten animals in each treatment were killed after 7 days, 15 days and 30 days. The radiographic and histometric values were statistically analyzed. In all groups radiographic and histometric analysis showed less bone loss (P < 0.05) in animals treated with SRP + LLLT in all experimental periods. SRP + LLLT was an effective adjuvant conventional treatment for periodontitis in rats treated with dexamethasone.
本研究旨在比较低水平激光疗法（LLLT）作为佐剂治疗地塞米松诱导的牙周炎与刮治和根面平整（SRP）的疗效。将 120 只大鼠分为两组：D 组（n = 60），用地塞米松处理；ND 组（n = 60），用生理盐水处理。两组动物均在左侧第一下颌磨牙上结扎以诱导牙周病。7 天后，去除结扎线，所有动物均接受 SRP，并根据以下治疗方法进行分组：SRP，生理盐水冲洗（SS）；SRP+LLLT，SS 和激光照射（660nm；24J；0.428W/cm(2)）。每组各有 10 只动物在 7 天、15 天和 30 天后处死。对影像学和组织学测量值进行了统计学分析。在所有组中，影像学和组织学分析均显示在所有实验期间接受 SRP+LLLT 治疗的动物的骨丢失较少（P < 0.05）。SRP+LLLT 是地塞米松治疗大鼠牙周炎的有效常规治疗佐剂。
