HCV 治疗决策中的物质使用体验与 HIV/HCV 合并感染成年人的 HCV 治疗决策。

HCV treatment decision-making substance use experiences and hepatitis C treatment decision-making among HIV/HCV Coinfected Adults.

机构信息

University of Massachusetts Worcester, Graduate School of Nursing, Worcester, Massachusetts 01655, USA.

出版信息

Subst Use Misuse. 2009;44(7):915-33. doi: 10.1080/10826080802486897.

PMID:19440928

Abstract

Hepatitis C virus (HCV) infection is a major source of morbidity and mortality among substance users and persons living with human immunodeficiency virus (HIV) infection. Treatment for chronic HCV infection involves complex decision-making. These decisions are even more complicated in persons with HIV and substance use related problems. A secondary analyses of qualitative data collected in the United States (2004-2005) with 31 HIV/HCV coinfected adults (48% women; mean age 44.7 years) revealed three themes related to substance use (substance use evolution, revolving door: going back out and reconstructing life) and two HCV treatment decision-making themes (HCV infection treatment issues: not a priority, fear, misinformation and get clean and try it). Study limitations and implications are discussed.

摘要

丙型肝炎病毒 (HCV) 感染是导致物质使用者和人类免疫缺陷病毒 (HIV) 感染者发病和死亡的主要原因。慢性 HCV 感染的治疗需要进行复杂的决策。对于 HIV 感染者和存在物质使用相关问题的患者，这些决策更加复杂。在美国（2004-2005 年）进行的一项对 31 名 HIV/HCV 合并感染者成年人（48%为女性；平均年龄 44.7 岁）的定性数据分析的二次分析中，揭示了与物质使用相关的三个主题（物质使用的演变、反复进出：重新开始和重建生活）和两个 HCV 治疗决策主题（HCV 感染治疗问题：不是优先事项、恐惧、错误信息和保持清洁并尝试治疗）。讨论了研究的局限性和意义。