Louie Brian, Lei John, Liska Sally, Dowling Teri, Pandori Mark W
San Francisco Department of Public Health Laboratory, 101 Grove Street, San Francisco, CA 94102, USA.
J Virol Methods. 2009 Jul;159(1):119-21. doi: 10.1016/j.jviromet.2009.02.016. Epub 2009 Feb 24.
The performances of three blood-based immunoassays test kits were compared with regard to their ability to detect HIV-1 antibody in oral fluid. It was found that these three kits differ in their ability to detect HIV-1 antibody. Notably, a third generation EIA which has been shown to possess superior sensitivity for antibody detection in plasma appears to possess no sensitivity advantage for detecting HIV-1 antibody in oral fluid.
比较了三种基于血液的免疫分析检测试剂盒在检测口腔液中HIV-1抗体方面的性能。发现这三种试剂盒在检测HIV-1抗体的能力上存在差异。值得注意的是，已证明在检测血浆中抗体时具有更高灵敏度的第三代酶免疫分析（EIA），在检测口腔液中的HIV-1抗体时似乎没有灵敏度优势。
