口腔液检测用于筛查人类免疫缺陷病毒暴露婴儿。
Oral fluid tests for screening of human immunodeficiency virus-exposed infants.
机构信息
Department of Molecular Medicine and Haematology, Medical School, University of the Witwatersrand, Parktown, Johannesburg, South Africa.
出版信息
Pediatr Infect Dis J. 2010 Feb;29(2):169-72. doi: 10.1097/INF.0b013e3181b9a19c.
In high human immunodeficiency virus (HIV) prevalence settings, routine screening of infants attending immunization visits could improve identification of HIV-exposed infants to receive an early diagnosis and appropriate interventions. This first assessment of 2 rapid oral fluid HIV tests in early infancy demonstrates a sensitivity of <90% for detection of HIV-exposure resulting in failure to detect at least 1 in 10 HIV-infected infants.
在人类免疫缺陷病毒（HIV）高发地区，对接受免疫接种的婴儿进行常规筛查，可以提高发现HIV 暴露婴儿的能力，以便及时做出诊断并采取适当的干预措施。本研究首次评估了两种快速口腔液 HIV 检测方法在婴儿早期的应用情况，结果显示，这些方法检测 HIV 暴露的灵敏度＜90%，导致至少 10 例 HIV 感染婴儿漏检。
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