Smolander Juhani, Leppäluoto Juhani, Westerlund Tarja, Oksa Juha, Dugue Benoit, Mikkelsson Marja, Ruokonen Aimo
ORTON Orthopaedic Hospital, Helsinki, Finland.
Cryobiology. 2009 Jun;58(3):275-8. doi: 10.1016/j.cryobiol.2009.02.001.
Cold therapy is used to relieve pain and inflammatory symptoms. Humoral changes may account for the pain alleviation related to the cold exposures. The aim of the present study was to examine the effects of two types of cold therapy, winter swimming in ice-cold water (WS) and whole body cryotherapy (WBC), on the serum levels of the growth hormone, prolactin, thyrotropin and free fractions of thyroid hormones (fT3, fT4). One group of healthy females (n = 6) was exposed to WS (water 0-2 degrees C) for 20 s and another group (n = 6) to WBC (air 110 degrees C) for 2 min, three times a week for 12 weeks. Blood samples used for the hormone measurements were taken on weeks 1, 4 and 12 before and 35 min after the cold exposures and on the days of the respective weeks, when the cold exposures were not performed. During the WS treatments, serum thyrotropin increased significantly at 35 min on weeks 1 (p < 0.01) and 4 (p < 0.05), but the responses were within the health-related reference interval. During the WS, the serum prolactin measured at 35 min on week 12 was lower than during the control treatment, and no changes in fT3 or fT4 were observed. During the WBC, no changes in the serum levels of the studied hormones were observed during the 12 weeks. In conclusion, repeated WS and WBC treatments for healthy females do not lead to disorders related to altered secretions of the growth hormone, prolactin, thyrotropin, or thyroid hormones.
冷疗法用于缓解疼痛和炎症症状。体液变化可能是寒冷暴露相关疼痛减轻的原因。本研究的目的是检验两种冷疗法，即冷水冬泳（WS）和全身冷冻疗法（WBC），对生长激素、催乳素、促甲状腺激素以及甲状腺激素游离部分（fT3、fT4）血清水平的影响。一组健康女性（n = 6）暴露于0至2摄氏度的冷水中进行20秒的冷水冬泳，另一组（n = 6）暴露于零下110摄氏度的空气中进行2分钟的全身冷冻疗法，每周三次，共12周。用于激素测量的血样在第1、4和12周的冷暴露前、冷暴露后35分钟以及未进行冷暴露的各周当天采集。在冷水冬泳治疗期间，第1周（p < 0.01）和第4周（p < 0.05）冷暴露后35分钟时血清促甲状腺激素显著升高，但这些反应均在与健康相关的参考区间内。在冷水冬泳期间，第12周冷暴露后35分钟测得的血清催乳素低于对照治疗期间，且未观察到fT3或fT4有变化。在全身冷冻疗法期间，12周内所研究激素的血清水平未观察到变化。总之，对健康女性重复进行冷水冬泳和全身冷冻疗法不会导致与生长激素、催乳素、促甲状腺激素或甲状腺激素分泌改变相关的紊乱。
