Suppr超能文献

[从巴西南部医院污水中分离出的不动杆菌属细菌对β-内酰胺类抗生素的耐药性]

[Resistance to beta-lactams among Acinetobacter spp isolated from hospital sewage in southern Brazil].

作者信息

Gusatti Carolina de Souza, Ferreira Alessandra Einsfeld, Fuentefria Daiane Bopp, Corção Gertrudes

机构信息

Departamento de Microbiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS.

出版信息

Rev Soc Bras Med Trop. 2009 Mar-Apr;42(2):183-7. doi: 10.1590/s0037-86822009000200018.

Abstract

Acinetobacter spp is an important pathogen that is responsible for nosocomial infections affecting immunocompromised patients, and it can easily acquire resistance to antimicrobial agents. Hospital sewage is an important means for disseminating genes for resistance to antimicrobial agents, to the microbiota of the environment. Within this context, 30 strains of Acinetobacter spp from the sewage of a hospital in Porto Alegre, Rio Grande do Sul, were analyzed regarding their profile of susceptibility to beta-lactams, quinolones and aminoglycosides, by means of an antibiogram and tests to screen for metallo-beta-lactamases and extended-spectrum beta-lactamases. The profile obtained revealed the presence of multidrug-resistant strains and showed that resistance mechanisms such as the production of extended-spectrum beta-lactamases and efflux pumps may be present in these strains.

摘要

不动杆菌属是一种重要的病原体,可导致医院感染,影响免疫功能低下的患者,并且它很容易获得对抗菌药物的耐药性。医院污水是抗菌药物耐药基因向环境微生物群传播的重要途径。在此背景下,通过抗菌谱分析以及金属β-内酰胺酶和超广谱β-内酰胺酶的筛选试验,对巴西南部阿雷格里港一家医院污水中的30株不动杆菌属菌株进行了β-内酰胺类、喹诺酮类和氨基糖苷类药物敏感性分析。所得结果显示存在多重耐药菌株,并表明这些菌株可能存在超广谱β-内酰胺酶产生和外排泵等耐药机制。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验