烯炔硼酸酯与斯德酮环加成反应的范围和区域化学研究。
Investigation of the scope and regiochemistry of alkynylboronate cycloadditions with sydnones.
作者信息
Browne Duncan L, Vivat Jérôme F, Plant Andrew, Gomez-Bengoa Enrique, Harrity Joseph P A
机构信息
Department of Chemistry, University of Sheffield, Sheffield S3 7HF, United Kingdom.
出版信息
J Am Chem Soc. 2009 Jun 10;131(22):7762-9. doi: 10.1021/ja902460n.
PMID:19449876
Abstract
The cycloaddition of alkynylboronates and sydnones provides a convenient and highly regioselective method for the synthesis of a broad range of di-, tri-, and tetrasubstituted pyrazole boronic esters. The origins of an observed regiochemical divergence in the reactions of terminal alkynylboronates with their more substituted analogues have been studied by DFT methods.
摘要
炔基硼酸酯与烯二唑的环加成反应为合成多种二取代、三取代和四取代吡唑硼酸酯提供了一种简便且具有高度区域选择性的方法。通过密度泛函理论（DFT）方法研究了末端炔基硼酸酯与其取代程度更高的类似物反应中观察到的区域化学差异的起源。
Zotero 插件