抗磷脂（休斯）综合征：超越妊娠并发症和血栓形成
Antiphospholipid (Hughes) syndrome: beyond pregnancy morbidity and thrombosis.
作者信息
Mialdea Maria, Sangle Shirish R, D'Cruz David P
机构信息
The Lupus Research Unit, The Rayne Institute, 4thFloor, Lambeth Wing, St. Thomas' Hospital, London SE17EH, UK.
出版信息
J Autoimmune Dis. 2009 May 19;6:3. doi: 10.1186/1740-2557-6-3.
Abstract
The antiphospholipid syndrome is an autoimmune disease characterised by recurrent arterial or venous thrombosis, pregnancy morbidity and the persistence of positive antiphospholipid antibodies. Many other clinical manifestations may occur including heart valve disease, livedo reticularis, thrombocytopenia and neurological manifestations such as migraine and seizures. We review a number of other manifestations including stenotic lesions, coronary artery disease and accelerated atherosclerosis, skeletal disorders and the concept of seronegative antiphospholipid syndrome.
摘要
抗磷脂综合征是一种自身免疫性疾病，其特征为反复发生动脉或静脉血栓形成、妊娠并发症以及抗磷脂抗体持续呈阳性。还可能出现许多其他临床表现，包括心脏瓣膜病、网状青斑、血小板减少以及偏头痛和癫痫发作等神经系统表现。我们回顾了一些其他表现，包括狭窄性病变、冠状动脉疾病和动脉粥样硬化加速、骨骼疾病以及血清阴性抗磷脂综合征的概念。
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本文引用的文献
1
Syndrome X (angina pectoris with normal coronary arteries) and myocardial infarction in patients with anti-phospholipid (Hughes) syndrome.
Lupus. 2008 Feb;17(2):83-5. doi: 10.1177/0961203307086036.
2
Cutaneous manifestations of antiphospholipid antibody syndrome.
Hematol Oncol Clin North Am. 2008 Feb;22(1):67-77, vi. doi: 10.1016/j.hoc.2007.10.011.
3
The point prevalence of an abnormal ankle-brachial index in antiphospholipid antibody negative patients with livedo reticularis: a controlled study.
Ann Rheum Dis. 2008 Feb;67(2):276-7. doi: 10.1136/ard.2007.074567.
4
Subclinical atherosclerosis in primary antiphospholipid syndrome.
Ann N Y Acad Sci. 2007 Jun;1108:475-80. doi: 10.1196/annals.1422.050.
5
Criteria for the diagnosis of antiphospholipid syndrome in patients presenting with dermatologic symptoms.
J Am Acad Dermatol. 2007 Jul;57(1):112-5. doi: 10.1016/j.jaad.2006.11.033. Epub 2007 Apr 30.
6
Vasculopathy and arterial stenotic lesions in the antiphospholipid syndrome.
Rheumatology (Oxford). 2007 Jun;46(6):907-10. doi: 10.1093/rheumatology/kem040. Epub 2007 Apr 2.
7
Myocardial infarction in young patients without coronary atherosclerosis: assume primary antiphospholipid syndrome until proved otherwise.
Int J Clin Pract. 2007 Mar;61(3):379-84. doi: 10.1111/j.1742-1241.2006.01245.x.
8
Cognitive deficits in patients with antiphospholipid syndrome: association with clinical, laboratory, and brain magnetic resonance imaging findings.
Arch Intern Med. 2006 Nov 13;166(20):2278-84. doi: 10.1001/archinte.166.20.2278.
9
Chorea and rapidly progressive subcortical dementia in antiphospholipid syndrome.
J Clin Rheumatol. 2002 Dec;8(6):332-9. doi: 10.1097/00124743-200212000-00010.
10
Treatment of mesenteric angina with prolonged anticoagulation in a patient with antiphospholipid (Hughes) syndrome and coeliac artery stenosis.
Ann Rheum Dis. 2006 Oct;65(10):1398-9. doi: 10.1136/ard.2005.050344.
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