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老年人退行性腰椎间盘和小关节疾病:患病率及临床相关性

Degenerative lumbar disc and facet disease in older adults: prevalence and clinical correlates.

作者信息

Hicks Gregory E, Morone Natalia, Weiner Debra K

机构信息

Department of Physical Therapy, University of Delaware, Newark, DE 19716, USA.

出版信息

Spine (Phila Pa 1976). 2009 May 20;34(12):1301-6. doi: 10.1097/BRS.0b013e3181a18263.

Abstract

STUDY DESIGN

A case-control study of older adults with and without chronic low back pain (CLBP).

OBJECTIVE

Compare and describe the radiographic severity of degenerative disc and facet disease in the lumbosacral spine of community-dwelling older adults with and without CLBP and to examine the relationship between spinal pathology and pain.

SUMMARY OF BACKGROUND DATA

Degenerative spinal pathology is often implicated as the primary reason for CLBP in older adults. Despite evidence that spinal pathology may be ubiquitous in older adults regardless of pain status, radiography continues to be heavily used in the diagnostic process.

METHODS

Participants in this case-control study included 162 older adults (> or =65) with CLBP and an age and gender matched pain-free group of 158 people. CLBP was characterized as pain of at least moderate intensity occurring daily or almost everyday for at least 3 months. Radiographic severity of disc and facet disease was graded using a reliable and valid system.

RESULTS

Results demonstrated that the presence of degenerative disc and facet pathology in older adults is ubiquitous, regardless of clinical status, with greater than 90% demonstrating some level of degeneration. Higher radiographic severity scores were associated with the presence of CLBP. In fact, presence of severe disc pathology was associated with 2-fold greater odds of having CLBP. But, radiographic severity of disc and facet disease was not associated with pain severity among those with CLBP.

CONCLUSION

From a research perspective, radiographic evaluation of spinal pathology provides additional information about older adults with CLBP compared to pain-free individuals, but its clinical utility for diagnostic purposes is still in question.

摘要

研究设计

一项针对患有和未患有慢性下腰痛(CLBP)的老年人的病例对照研究。

目的

比较并描述社区居住的患有和未患有CLBP的老年人腰骶椎椎间盘退变和小关节疾病的影像学严重程度,并研究脊柱病理与疼痛之间的关系。

背景数据总结

退行性脊柱病理常被认为是老年人CLBP的主要原因。尽管有证据表明无论疼痛状况如何,脊柱病理在老年人中可能普遍存在,但X线摄影在诊断过程中仍被大量使用。

方法

本病例对照研究的参与者包括162名患有CLBP的老年人(≥65岁)以及158名年龄和性别匹配的无疼痛组人群。CLBP的特征为至少中度强度的疼痛,每天或几乎每天发生,持续至少3个月。使用可靠且有效的系统对椎间盘和小关节疾病的影像学严重程度进行分级。

结果

结果表明,无论临床状态如何,老年人中椎间盘退变和小关节病理的存在都很普遍,超过90%的人表现出一定程度的退变。较高的影像学严重程度评分与CLBP的存在相关。事实上,严重椎间盘病理的存在与患CLBP的几率高出2倍相关。但是,在患有CLBP的人群中,椎间盘和小关节疾病的影像学严重程度与疼痛严重程度无关。

结论

从研究角度来看,与无疼痛个体相比,脊柱病理的影像学评估为患有CLBP的老年人提供了额外信息,但其在诊断目的方面的临床实用性仍存在疑问。

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