Wender E H, Solanto M V
Schneider Children's Hospital, Long Island Jewish Medical Center, New Hyde Park, New York 11042.
Pediatrics. 1991 Nov;88(5):960-6.
Foods high in refined sugar are claimed to exacerbate hyperactivity and increase aggressive behavior. Controlled studies have failed to confirm any effect on hyperactivity and effects on inattention have been equivocal. Possible effect on aggressive behavior has received little study. This study assessed cognitive attention and aggressive behavior immediately following an acute ingestion of sugar compared with saccharin and aspartame-sweetened placebos in 17 subjects with attention deficit disorder with hyperactivity compared with 9 age-matched control subjects. The sugar and placebo challenges were given with a breakfast high in carbohydrate. Although the children with attention deficit disorder with hyperactivity were significantly more aggressive than the control subjects, there were no significant effects of sugar or either placebo on the aggressive behavior of either group. However, inattention, as measured by a continuous performance task, increased only in the attention deficit disorder with hyperactivity group following sugar, but not saccharin or aspartame. This result is of questionable clinical significance inasmuch as aggressive behavior was unchanged. The finding may be due to the combination of the sugar challenge with a high-carbohydrate breakfast. These findings should be replicated and any possible clinical significance should be documented before any dietary recommendations can be made.
据称，高糖精制食品会加剧多动症状并增加攻击性行为。对照研究未能证实其对多动症状有任何影响，对注意力不集中的影响也尚无定论。对攻击性行为的可能影响则鲜有研究。本研究评估了17名患有注意力缺陷多动障碍的受试者和9名年龄匹配的对照受试者在急性摄入糖、糖精和阿斯巴甜甜味安慰剂后即刻的认知注意力和攻击性行为。糖和安慰剂挑战均与高碳水化合物早餐一起进行。尽管患有注意力缺陷多动障碍的儿童比对照受试者更具攻击性，但糖或任何一种安慰剂对两组的攻击性行为均无显著影响。然而，通过连续操作任务测量，仅患有注意力缺陷多动障碍的儿童在摄入糖后注意力不集中情况增加，而摄入糖精或阿斯巴甜后未增加。鉴于攻击性行为未改变，这一结果的临床意义存疑。这一发现可能是由于糖挑战与高碳水化合物早餐共同作用所致。在提出任何饮食建议之前，这些发现都应重复验证，并记录任何可能的临床意义。
