来自毛叶吴茱萸的γ-内酯咔唑类化合物。
Gamma-lactone carbazoles from Clausena anisata.
作者信息
Ito Chihiro, Itoigawa Masataka, Aizawa Kie, Yoshida Keisuke, Ruangrungsi Nijsiri, Furukawa Hiroshi
机构信息
Faculty of Pharmacy, Meijo University, Tempaku, Nagoya, Japan.
出版信息
J Nat Prod. 2009 Jun;72(6):1202-4. doi: 10.1021/np800735m.
PMID:19459693
Abstract
The study of chemical constituents of the stems of Clausena anisata collected in Thailand led to the isolation and identification of eight known and two new carbazole alkaloids named furanoclausamines A (1) and B (2). Clausamine E (3) was found to exhibit cytotoxicity against the human leukemia cell line HL-60.
摘要
对采自泰国的香椒茎的化学成分进行研究，从而分离并鉴定出8种已知的咔唑生物碱以及2种新的咔唑生物碱，分别命名为呋喃香椒胺A（1）和B（2）。发现香椒胺E（3）对人白血病细胞系HL-60具有细胞毒性。
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