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新生儿体外膜肺氧合的患者选择:超越疾病严重程度。

Patient selection for neonatal extracorporeal membrane oxygenation: beyond severity of illness.

作者信息

Chapman R L, Peterec S M, Bizzarro M J, Mercurio M R

机构信息

Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520-5426, USA.

出版信息

J Perinatol. 2009 Sep;29(9):606-11. doi: 10.1038/jp.2009.57. Epub 2009 May 21.

Abstract

OBJECTIVE

To explore how neonates with respiratory failure are selected for extracorporeal membrane oxygenation (ECMO) once severity of illness criteria are met, and to determine how conflicts between ECMO providers and parents over the initiation of ECMO are addressed.

STUDY DESIGN

A cross-sectional study was conducted using a data collection survey, which was sent to the directors of neonatal respiratory ECMO centers.

RESULT

The lowest birth weight and gestational age at which respondents would consider placing a neonate on ECMO were frequently below recommended thresholds. There was wide variability in respondents' willingness to place neonates on ECMO in the presence of conditions such as intraventricular hemorrhage and hypoxic ischemic encephalopathy. The number of respondents who would never seek to override parental refusal of ECMO was equal to the number who would always do so.

CONCLUSION

Significant variability exists in the selection criteria for neonatal ECMO and in how conflicts with parents over the provision of ECMO are resolved.

摘要

目的

探讨一旦满足疾病严重程度标准,如何选择患有呼吸衰竭的新生儿进行体外膜肺氧合(ECMO)治疗,并确定如何解决ECMO提供者与父母之间在启动ECMO治疗方面的冲突。

研究设计

采用数据收集调查进行横断面研究,该调查发送给了新生儿呼吸ECMO中心的主任。

结果

受访者考虑将新生儿置于ECMO治疗的最低出生体重和胎龄经常低于推荐阈值。在存在脑室内出血和缺氧缺血性脑病等情况时,受访者将新生儿置于ECMO治疗的意愿存在很大差异。永远不会试图推翻父母拒绝ECMO治疗的受访者数量与总是会这样做的受访者数量相等。

结论

新生儿ECMO的选择标准以及在提供ECMO治疗方面与父母的冲突解决方式存在显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0d/2834372/ae2674fb52b8/jp200957f1.jpg

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