Fitouri Zouheir, Nouira Yassine, Nouira Kaïes, Sallami Sataa, Hmidi Mohamed, El Fekih Nizar, Horchani Ali
Department of Urology, La Rabta hospital, Tunis, Tunisia.
Tunis Med. 2008 Oct;86(10):912-5.
Focal xanthogranulomatous pyelonephritis is an atypical form of chronic renal infection. It is frequently misdiagnosed preoperatively because of its resemblance to malignancy.
We report on a fifty-year-old woman who presented with a right kidney mass. The CT scan showed a solid renal mass with a lithiasis of the upper ureter. The diagnosis of focal xanthogranulomatous pyelonephritis was suspected by clinical and radiological findings and confirmed by histopathologic examination of percutaneous biopsy specimens of the lesion. Successful treatement of the patient was achieved with removal of the lithiasis and antibiotic therapy during eight weeks. Three months later the CT scan was completely normal.
The conservative treatment of focal xanthogranulomatous pyelonephritis makes possible to avoid a needless nephrectomy usually on young patients. However a close follow-up must be undergone on these patients because of the possible association of focal xanthogranulomatous pyelonephritis and renal cell carcinoma of the kidney.
局灶性黄色肉芽肿性肾盂肾炎是一种非典型的慢性肾脏感染形式。由于其与恶性肿瘤相似,术前常被误诊。
我们报告一名50岁女性,她出现右肾肿块。CT扫描显示一个实性肾肿块,伴有上段输尿管结石。根据临床和影像学表现怀疑为局灶性黄色肉芽肿性肾盂肾炎,并通过病变经皮活检标本的组织病理学检查得以确诊。通过去除结石并进行为期八周的抗生素治疗,成功治愈了该患者。三个月后CT扫描完全正常。
局灶性黄色肉芽肿性肾盂肾炎的保守治疗使得通常在年轻患者中避免不必要的肾切除术成为可能。然而,由于局灶性黄色肉芽肿性肾盂肾炎与肾细胞癌可能存在关联,必须对这些患者进行密切随访。