人类中的猴疟：实验室数据相互矛盾导致的诊断难题。

Monkey malaria in humans: a diagnostic dilemma with conflicting laboratory data.

作者信息

Ong Catherine W M, Lee Shir Ying, Koh Wee Hong, Ooi Eng-Eong, Tambyah Paul A

机构信息

National University Health System, Singapore; Defence Medical and Environmental Research Institute, Singapore.

出版信息

Am J Trop Med Hyg. 2009 Jun;80(6):927-8.

PMID:19478250

Abstract

Plasmodium knowlesi has recently been recognized as the fifth Plasmodium species causing malaria in humans. Diagnosis is difficult morphologically, and currently, available rapid tests have not been comprehensively evaluated with this pathogen. We report a case of P. knowlesi malaria that was confirmed after the initial clue of discordant microscopy and immunochromatographic results, highlighting the importance of molecular diagnostics in cases with the relevant clinical and epidemiologic history.

摘要

诺氏疟原虫最近被确认为引起人类疟疾的第五种疟原虫。其形态学诊断困难，目前现有的快速检测方法尚未对该病原体进行全面评估。我们报告了一例诺氏疟原虫疟疾病例，该病例在显微镜检查和免疫层析结果不一致这一初步线索后得到确诊，突出了分子诊断在具有相关临床和流行病学病史病例中的重要性。