Setiadi Wuryantari, Sudoyo Herawati, Trimarsanto Hidayat, Sihite Boy Adventus, Saragih Riahdo Juliarman, Juliawaty Rita, Wangsamuda Suradi, Asih Puji Budi Setia, Syafruddin Din
Eijkman Institute for Molecular Biology, Jakarta, Indonesia.
Muara Teweh Secondary Referral Hospital, Barito Utara Regency, Muara Teweh, Central Kalimantan, Indonesia.
Malar J. 2016 Apr 16;15:218. doi: 10.1186/s12936-016-1272-z.
The Indonesian archipelago is endemic for malaria. Although Plasmodium falciparum and P. vivax are the most common causes for malaria cases, P. malariae and P. ovale are also present in certain regions. Zoonotic case of malaria had just became the attention of public health communities after the Serawak study in 2004. However, zoonotic case in Indonesia is still under reported; only one published report of knowlesi malaria in South Kalimantan in 2010.
A case of Plasmodium knowlesi infection in a worker from a charcoal mining company in Central Kalimantan, Indonesia was described. The worker suffered from fever following his visit to a lowland forest being cut and converted into a new mining location.
This study confirmed a zoonotic infection using polymerase chain reaction amplification and Sanger sequencing of plasmodial DNA encoding the mitochondrial cytochrome c oxidase subunit I (mtCOI).
印度尼西亚群岛是疟疾的地方性流行区。虽然恶性疟原虫和间日疟原虫是疟疾病例最常见的病因，但三日疟原虫和卵形疟原虫在某些地区也有出现。2004年砂拉越研究之后，人兽共患疟疾病例才开始受到公共卫生界的关注。然而，印度尼西亚的人兽共患疟疾病例报告仍然不足；2010年南加里曼丹仅有一篇关于诺氏疟原虫疟疾的已发表报告。
描述了印度尼西亚中加里曼丹一家木炭开采公司一名工人感染诺氏疟原虫的病例。该工人在前往一片被砍伐并改造成新矿区的低地森林后出现发热症状。
本研究通过对编码线粒体细胞色素c氧化酶亚基I（mtCOI）的疟原虫DNA进行聚合酶链反应扩增和桑格测序，证实了这是人兽共患感染。
