Nicol Malcolm, Sun Yu, Craig Niall, Wardlaw Douglas
Department of Orthopaedics, Grampian Hospitals NHS Trust, Aberdeen, UK.
Eur Spine J. 2009 Oct;18(10):1548-52. doi: 10.1007/s00586-009-1035-4. Epub 2009 May 30.
Deep venous thrombosis (DVT) and pulmonary embolism (PE) cause significant morbidity and mortality in orthopaedic surgical practice, although the incidence following surgery to the lumbosacral spine is less than following lower limb surgery. Our objective was to compare our rate of thromboembolic complications with those published elsewhere and investigate whether the adoption of additional pharmacological measures reduced the incidence of clinically evident DVT and PE. This retrospective study was undertaken to investigate the incidence of DVT/PE during the 10 years from 1 January 1985 to 31 December 1994, and then to assess the effectiveness of an anticoagulant policy introduced during 1995 using low dose aspirin or LMH in high risk cases. All records for spinal operations were reviewed for thrombo-embolic complications by reference to the Scottish Morbidity Record form SMR1. To ensure that all patients were compliant with the policy, data for the whole of 1995 was omitted and the period 1 January 1996 to 31 December 2003 was taken to assess its effectiveness. Surgery was done with the patient in the kneeling, seated prone position which leaves the abdomen free and avoids venous kinking in the legs. Records of a total of 1,111 lumbar spine operations were performed from 1 January 1985 to 31 December 2004 were reviewed. The overall incidence of thrombo-embolic complications was 0.29%. A total of 697 operations were performed from 1 January 1985 to 31 December 1994 with two cases of DVT and no cases of PE giving thromboembolic complication rate of 0.29%. During the period 1 January 1996 to 31 December 2003, 414 operations resulted in one case of DVT and no cases of PE, a rate of 0.24%. The incidence of symptomatic thrombo-embolic complications in lumbar spinal surgery is low in the kneeling, seated prone operating position, whether or not anticoagulation is used.
在骨科手术中,深静脉血栓形成(DVT)和肺栓塞(PE)会导致显著的发病率和死亡率,尽管腰骶部脊柱手术后的发病率低于下肢手术后的发病率。我们的目的是将我们的血栓栓塞并发症发生率与其他地方公布的发生率进行比较,并调查采取额外的药物措施是否能降低临床明显的DVT和PE的发生率。这项回顾性研究旨在调查1985年1月1日至1994年12月31日这10年间DVT/PE的发生率,然后评估1995年引入的一项抗凝策略在高危病例中使用低剂量阿司匹林或低分子肝素(LMH)的有效性。通过参考苏格兰发病率记录表SMR1,对所有脊柱手术记录进行血栓栓塞并发症审查。为确保所有患者都遵守该策略,1995年全年的数据被省略,采用1996年1月1日至2003年12月31日这段时间来评估其有效性。手术时患者采用跪姿、坐位俯卧位,这样腹部不受压且避免腿部静脉扭曲。回顾了1985年1月1日至2004年12月31日期间总共1111例腰椎手术的记录。血栓栓塞并发症的总体发生率为0.29%。1985年1月1日至1994年12月31日期间共进行了697例手术,有2例DVT,无PE病例,血栓栓塞并发症发生率为0.29%。在1996年1月1日至2003年12月31日期间,414例手术中有1例DVT,无PE病例,发生率为0.24%。无论是否使用抗凝治疗,在跪姿、坐位俯卧位的腰椎手术中,有症状的血栓栓塞并发症发生率都很低。