Urban Katelyn, Chu Sherman, Giesey Rachel L, Mehrmal Sino, Uppal Prabhdeep, Delost Maria E, Delost Gregory R
Lake Erie College of Osteopathic Medicine, Greensburg, Pennsylvania.
Western University of Health Sciences, College of Osteopathic Medicine of the Pacific, Northwest, Lebanon, Oregon.
JAAD Int. 2020 Dec 10;2:40-50. doi: 10.1016/j.jdin.2020.10.006. eCollection 2021 Mar.
Skin diseases have a significant global impact on quality of life, mental health, and loss of income. The burden of dermatologic conditions and its relationship with socioeconomic status in Asia is currently not well understood.
We selected Global Burden of Disease Study datasets to analyze disability-adjusted life years (DALYs) in 50 Asian countries, including Central Asia, northern Asia, eastern Asia, western Asia, southeastern Asia, and southern Asia, between 1990 and 2017. We compared DALYs to the socioeconomic status using the sociodemographic index and gross domestic product per capita of a country. Statistical analysis was performed using Pearson's correlation.
Some countries had higher or lower than expected age-standardized DALY rates of skin diseases. Asian countries, especially high-income countries, had a high burden of inflammatory dermatoses, including acne, alopecia areata, atopic dermatitis, contact dermatitis, decubitus ulcers, psoriasis, pruritus, and seborrheic dermatitis. The burden of infectious dermatoses was greater in low-income Asian countries. The burden of skin cancer in Asia was relatively low.
There is a high burden of skin disease, especially inflammatory conditions, in Asian countries, but the burden of individual dermatoses in Asia varies by country and socioeconomic status. DALYs can potentially serve as a purposeful measure for directing resources to improve the burden of skin disease in Asia.
皮肤疾病对全球生活质量、心理健康和收入损失有着重大影响。目前，亚洲皮肤病负担及其与社会经济地位的关系尚未得到充分了解。
我们选取了全球疾病负担研究数据集，以分析1990年至2017年间50个亚洲国家（包括中亚、北亚、东亚、西亚、东南亚和南亚）的伤残调整生命年（DALYs）。我们使用社会人口指数和一个国家的人均国内生产总值将伤残调整生命年与社会经济地位进行比较。采用Pearson相关性进行统计分析。
一些国家的皮肤病年龄标准化伤残调整生命年率高于或低于预期。亚洲国家，尤其是高收入国家，炎性皮肤病负担较高，包括痤疮、斑秃、特应性皮炎、接触性皮炎、褥疮、银屑病、瘙痒症和脂溢性皮炎。低收入亚洲国家的感染性皮肤病负担更大。亚洲的皮肤癌负担相对较低。
亚洲国家皮肤病负担较重，尤其是炎性疾病，但亚洲各国皮肤病负担因国家和社会经济地位而异。伤残调整生命年有可能作为一种有针对性的衡量指标，用于指导资源配置以改善亚洲的皮肤病负担。
