Mohammadi Zahed
Department of Endodontics, Sadoughi University of Medical Sciences, Yazd, Iran.
J Calif Dent Assoc. 2009 Feb;37(2):98-108.
Antibiotics are an extremely valuable addition to the armamentarium available to health practitioners for management of bacterial infections. Due to the potential risk of adverse systemic effects of systemic applications and ineffectiveness of systemic antibiotics in the necrotic pulpless tooth and the periradicular tissues, local application of antibiotics may be a more effective mode for delivering antibiotics to infected root canals. This paper reviews the history, rationale, and applications of antibiotics and antibiotics-containing medicaments in endodontics.
抗生素是医疗从业者用于治疗细菌感染的极为宝贵的药物。由于全身应用抗生素存在潜在的全身不良反应风险，且全身用抗生素对坏死无髓牙及根尖周组织无效，局部应用抗生素可能是将抗生素输送至感染根管的更有效方式。本文综述了抗生素及含抗生素药物在牙髓病学中的历史、原理及应用。
