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腹腔镜保留直肠全结肠切除术的中期功能结局:40例连续病例的前瞻性研究

Mid-term functional outcome of laparoscopic restorative proctocolectomy: a prospective study of 40 consecutive cases.

作者信息

Berdah Stephane V, Mardion Rémi Bon, Grimaud Jean-Charles, Barthet Marc, Orsoni Pierre, Moutardier Vincent, Brunet Christian

机构信息

Department of Digestive Diseases, Hôpital Nord, Marseille, France.

出版信息

J Laparoendosc Adv Surg Tech A. 2009 Aug;19(4):485-8. doi: 10.1089/lap.2008.0390.

Abstract

INTRODUCTION

This prospective study aimed to analyze the functional outcome after a two-stage laparoscopic total proctocolectomy with ileal pouch-anal anastomosis.

MATERIALS AND METHODS

From May 1999 to May 2008, 68 consecutive two-stage laparoscopic total proctocolectomies with ileal pouch-anal anastomosis were performed (ulcerative colitis: n = 61; familial adenomatous polyposis: n = 7). A covering ileostomy was used in all patients. Forty patients whose covering ileostomy had been closed for a minimum of 2 years were included in this series.

RESULTS

Conversion to laparotomy was necessary in 4 of 40 patients (10%). Thirteen postoperative complications occurred in 13 of 40 patients (30%). At a median follow-up of 38 months (range, 26-90), the median number of bowel movements was 4 per 24 hours (range, 2-10); 15 patients (38%) had no nighttime bowel movements. None of the patients had fecal incontinence or urgency. Thirty-four of the 40 patients (85%) experienced no soiling. Seven patients (18%) took regular antidiarrheal medication. All patients were able to resume all activities practiced prior to illness onset, and 36 of 40 (90%) were satisfied with their overall quality of life (very good or good).

CONCLUSION

Laparoscopic total proctocolectomy with ileal pouch-anal anastomosis provides satisfying mid-term functional outcome.

摘要

引言

本前瞻性研究旨在分析两阶段腹腔镜全直肠系膜切除回肠储袋肛管吻合术后的功能结局。

材料与方法

1999年5月至2008年5月,连续进行了68例两阶段腹腔镜全直肠系膜切除回肠储袋肛管吻合术(溃疡性结肠炎:n = 61;家族性腺瘤性息肉病:n = 7)。所有患者均采用覆盖式回肠造口术。本系列纳入了40例覆盖式回肠造口已关闭至少2年的患者。

结果

40例患者中有4例(10%)需要转为开腹手术。40例患者中有13例(30%)发生了13例术后并发症。中位随访38个月(范围26 - 90个月),24小时排便中位数为4次(范围2 - 10次);15例患者(38%)夜间无排便。所有患者均无大便失禁或便急。40例患者中有34例(85%)无污粪现象。7例患者(18%)规律服用止泻药。所有患者均能够恢复发病前进行的所有活动,40例中有36例(90%)对其总体生活质量满意(非常好或好)。

结论

腹腔镜全直肠系膜切除回肠储袋肛管吻合术提供了令人满意的中期功能结局。

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