Harpster N K
Angell Memorial Animal Hospital, Boston, Massachusetts.
Vet Clin North Am Small Anim Pract. 1991 Sep;21(5):989-1004. doi: 10.1016/s0195-5616(91)50107-8.
Antiarrhythmic therapy for Boxer cardiomyopathy both enhances the quality of life and improves life expectancy. The natural course of the disease for most dogs is a progression from mild arrhythmias to serious, potentially life-threatening arrhythmias and eventually to CHF. This process may evolve over a period of months or even years; the factors responsible for the variable rate of progression from one dog to another are not well understood. Once heart failure occurs, the long-term prognosis is dismal, usually no better than 3 to 6 months. Whether the administration of L-carnitine will have a significant effect on functional improvement of the heart, as taurine in dilatative feline cardiomyopathy, awaits the long-term evaluation of this therapy.
针对拳师犬心肌病的抗心律失常治疗既能提高生活质量，又能延长预期寿命。大多数犬类该疾病的自然病程是从轻度心律失常发展为严重的、可能危及生命的心律失常，最终发展为充血性心力衰竭。这个过程可能会持续数月甚至数年；导致不同犬只病情进展速度不同的因素尚不清楚。一旦发生心力衰竭，长期预后很差，通常不超过3至6个月。左旋肉碱的给药是否会像扩张型猫心肌病中的牛磺酸那样对心脏功能改善产生显著影响，还有待对该疗法进行长期评估。
