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腹腔镜可调节胃束带术后半固体食物的胃排空及胃囊运动

Gastric emptying of semisolids and pouch motility following laparoscopic adjustable gastric banding.

作者信息

Tiktinsky Ekaterina, Lantsberg Leonid, Lantsberg Sophie, Mizrahi Solly, Agranotvich Svetlana, Friger Michael, Kirshtein Boris

机构信息

Departments of Nuclear Medicine, Soroka University Medical Center, Beer-Sheva, Israel.

出版信息

Obes Surg. 2009 Sep;19(9):1270-3. doi: 10.1007/s11695-009-9887-6. Epub 2009 Jun 5.

Abstract

BACKGROUND

Laparoscopic adjustable gastric banding (LAGB) has been popularized as an effective, safe, minimally invasive surgical technique for the treatment of morbid obesity. We performed a pilot study to evaluate gastric emptying of semisolid meals and antral motility following LAGB.

METHODS

Gastric emptying half-time was compared in normal volunteers and morbidly obese patients before and 6-12 months after LAGB using sulfur colloid-labeled semisolid meals.

RESULTS

There was no difference in mean age between groups. Women were prevalent in the group of obese patients. BMI was higher in patients before surgery (p < 0.001). Patients following LAGB demonstrated prolonged gastric pouch emptying (T1/2 = 36.6 +/- 9.8 min) compared to subjects without surgery (23.8 +/- 4.7 min) and healthy volunteers (22.8 +/- 6.8 min; p < 0.001). Similar gastric contractility was found all groups (3.3 +/- 0.4; p = 0.968). No cases of band slippage or pouch dilatation were observed during mean follow-up of 11.4 months.

CONCLUSIONS

A standard normal gastric pouch emptying rate of semisolids in asymptomatic patients after LAGB was established. Postoperative prolongation of gastric emptying is a matter of mechanical delay without gastric pouch denervation. This study provides a first step of future functional evaluation of complications following this type of bariatric surgery.

摘要

背景

腹腔镜可调节胃束带术(LAGB)已作为一种治疗病态肥胖的有效、安全、微创外科技术得到推广。我们进行了一项初步研究,以评估LAGB术后半固体食物的胃排空及胃窦动力。

方法

使用硫胶体标记的半固体食物,比较正常志愿者和病态肥胖患者在LAGB术前及术后6 - 12个月的胃排空半衰期。

结果

各组间平均年龄无差异。肥胖患者组中女性居多。术前患者的BMI更高(p < 0.001)。与未手术者(23.8 ± 4.7分钟)和健康志愿者(22.8 ± 6.8分钟;p < 0.001)相比,LAGB术后患者的胃囊排空时间延长(T1/2 = 36.6 ± 9.8分钟)。所有组的胃收缩性相似(3.3 ± 0.4;p = 0.968)。在平均11.4个月的随访期间,未观察到束带滑脱或胃囊扩张病例。

结论

确定了LAGB术后无症状患者半固体食物的标准正常胃囊排空率。术后胃排空延长是机械性延迟问题,不存在胃囊去神经支配。本研究为此类减肥手术术后并发症的未来功能评估迈出了第一步。

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