Tiktinsky Ekaterina, Lantsberg Leonid, Lantsberg Sophie, Mizrahi Solly, Agranotvich Svetlana, Friger Michael, Kirshtein Boris
Departments of Nuclear Medicine, Soroka University Medical Center, Beer-Sheva, Israel.
Obes Surg. 2009 Sep;19(9):1270-3. doi: 10.1007/s11695-009-9887-6. Epub 2009 Jun 5.
Laparoscopic adjustable gastric banding (LAGB) has been popularized as an effective, safe, minimally invasive surgical technique for the treatment of morbid obesity. We performed a pilot study to evaluate gastric emptying of semisolid meals and antral motility following LAGB.
Gastric emptying half-time was compared in normal volunteers and morbidly obese patients before and 6-12 months after LAGB using sulfur colloid-labeled semisolid meals.
There was no difference in mean age between groups. Women were prevalent in the group of obese patients. BMI was higher in patients before surgery (p < 0.001). Patients following LAGB demonstrated prolonged gastric pouch emptying (T1/2 = 36.6 +/- 9.8 min) compared to subjects without surgery (23.8 +/- 4.7 min) and healthy volunteers (22.8 +/- 6.8 min; p < 0.001). Similar gastric contractility was found all groups (3.3 +/- 0.4; p = 0.968). No cases of band slippage or pouch dilatation were observed during mean follow-up of 11.4 months.
A standard normal gastric pouch emptying rate of semisolids in asymptomatic patients after LAGB was established. Postoperative prolongation of gastric emptying is a matter of mechanical delay without gastric pouch denervation. This study provides a first step of future functional evaluation of complications following this type of bariatric surgery.
腹腔镜可调节胃束带术(LAGB)已作为一种治疗病态肥胖的有效、安全、微创外科技术得到推广。我们进行了一项初步研究,以评估LAGB术后半固体食物的胃排空及胃窦动力。
使用硫胶体标记的半固体食物,比较正常志愿者和病态肥胖患者在LAGB术前及术后6 - 12个月的胃排空半衰期。
各组间平均年龄无差异。肥胖患者组中女性居多。术前患者的BMI更高(p < 0.001)。与未手术者(23.8 ± 4.7分钟)和健康志愿者(22.8 ± 6.8分钟;p < 0.001)相比,LAGB术后患者的胃囊排空时间延长(T1/2 = 36.6 ± 9.8分钟)。所有组的胃收缩性相似(3.3 ± 0.4;p = 0.968)。在平均11.4个月的随访期间,未观察到束带滑脱或胃囊扩张病例。
确定了LAGB术后无症状患者半固体食物的标准正常胃囊排空率。术后胃排空延长是机械性延迟问题,不存在胃囊去神经支配。本研究为此类减肥手术术后并发症的未来功能评估迈出了第一步。