Li Mei, Hu Changwei, Gao Xiangyu, Xu Yue, Qian Xin, Brown Murray T, Cui Yibin
State Key Laboratory of Pollution Control and Resource Reuse and School of the Environment, Nanjing University, 22 Hankou Road, 210093 Nanjing, China.
Ecotoxicology. 2009 Aug;18(6):669-76. doi: 10.1007/s10646-009-0343-0. Epub 2009 Jun 4.
The potential toxicities of organic pollutants in the drinking water source at Meiliang Bay of Lake Taihu were investigated by comet assay and antioxidant enzyme approach on microalgae Euglena gracilis. The organic extracts of the water samples could induce DNA damage on microalgae cells. Statistically significant differences (P < 0.05) were observed at groups of 0.3x, 3x and 10x concentrations compared with the control and a solvent control (DMSO). The organic extracts also affected antioxidant enzyme activity and induced lipid peroxidation in the microalga. In the high dose group, there was an obvious increase in SOD content (P < 0.05). The results suggest that the concentrated organics from water sample extracts have adversary effects on E. gracilis and could possibly damage the ecosystem.
采用彗星试验和抗氧化酶法，以纤细裸藻为研究对象，对太湖梅梁湾饮用水源地有机污染物的潜在毒性进行了研究。水样的有机提取物可诱导微藻细胞的DNA损伤。与对照组和溶剂对照组（二甲基亚砜）相比，在0.3倍、3倍和10倍浓度组观察到具有统计学意义的差异（P < 0.05）。有机提取物还影响微藻的抗氧化酶活性并诱导脂质过氧化。在高剂量组中，超氧化物歧化酶含量明显增加（P < 0.05）。结果表明，水样提取物中的浓缩有机物对纤细裸藻有不利影响，并可能破坏生态系统。
