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Phosphoanalogues of amino acids involved in methionine metabolism as a new source of antiviral compounds.

作者信息

Khomutov R M, Shchipanova A I, Khurs E N

机构信息

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow 119991, Russia.

出版信息

Dokl Biochem Biophys. 2009 Mar-Apr;425:84-6. doi: 10.1134/s1607672909020070.

DOI:10.1134/s1607672909020070
PMID:19496328
Abstract
摘要

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本文引用的文献

1
Biologically active organophosphorous analogues of methionine in reactions catalyzed by L-methionine gamma-lyase.在L-蛋氨酸γ-裂解酶催化的反应中,蛋氨酸的生物活性有机磷类似物。
Dokl Biochem Biophys. 2006 Mar-Apr;407:102-5. doi: 10.1134/s1607672906020153.
2
Aminoalkythiophosphonates: a new type of biologically active compounds.氨基烷基硫代膦酸酯:一种新型生物活性化合物。
Dokl Biochem Biophys. 2005 May-Jun;402:181-3. doi: 10.1007/s10628-005-0065-z.
3
Synthesis of an alpha-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase.
Bioorg Med Chem Lett. 2002 Feb 11;12(3):457-60. doi: 10.1016/s0960-894x(01)00789-2.
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[Phosphinic analog of methionine inhibits growth of leucosis cell L1210 and transforms to phosphinic analog of S-adenosylmethionine].
Bioorg Khim. 2000 Sep;26(9):718-20.
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S-Adenosylmethionine and methylation.S-腺苷甲硫氨酸与甲基化作用
FASEB J. 1996 Mar;10(4):471-80.
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Human corneal epithelial primary cultures and cell lines with extended life span: in vitro model for ocular studies.人角膜上皮原代培养物和寿命延长的细胞系:眼部研究的体外模型。
Invest Ophthalmol Vis Sci. 1993 Nov;34(12):3429-41.
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L-2-Amino-4-methoxy-cis-but-3-enoic acid, a potent inhibitor of the enzymatic synthesis of S-adenosylmethionine.L-2-氨基-4-甲氧基-顺式-丁-3-烯酸,一种S-腺苷甲硫氨酸酶促合成的强效抑制剂。
Biochem Biophys Res Commun. 1982 May 31;106(2):251-5. doi: 10.1016/0006-291x(82)91102-0.
8
9-(trans-2',trans-3'-Dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine: analogs of neplanocin A which retain potent antiviral activity but exhibit reduced cytotoxicity.9-(反式-2',反式-3'-二羟基环戊-4'-烯基)腺嘌呤和-3-脱氮腺嘌呤:新制癌菌素A的类似物,保留了强大的抗病毒活性,但细胞毒性降低。
Antimicrob Agents Chemother. 1987 Nov;31(11):1849-51. doi: 10.1128/AAC.31.11.1849.
9
S-adenosyl-L-homocysteine hydrolase as a target for antiviral chemotherapy.
J Med Chem. 1991 May;34(5):1521-30. doi: 10.1021/jm00109a001.