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洗必泰/百里酚与含氟清漆联合使用对体弱的机构养老老年人根龋损害严重程度的影响。

The effects of the combination of chlorhexidine/thymol- and fluoride-containing varnishes on the severity of root caries lesions in frail institutionalised elderly people.

作者信息

Brailsford S R, Fiske J, Gilbert S, Clark D, Beighton D

机构信息

Dental Caries Research Group, GKT Dental Institute, Caldecot Road, Denmark Hill, London SE5 9RW, UK.

出版信息

J Dent. 2002 Sep-Nov;30(7-8):319-24. doi: 10.1016/s0300-5712(02)00045-3.

Abstract

OBJECTIVES

To compare the clinical effects of a fluoride-containing varnish (Fluor-Protector) in combination with a chlorhexidine-containing varnish (Cervitec) on existing root caries lesions in a group of frail elderly subjects.

METHODS

A randomised double blind longitudinal study was utilised. Subjects (n = 102) were randomly allocated to a Test or Placebo group. All leathery and soft root caries lesions in all subjects were coated with Fluor-Protector while the lesions in the Test group were also coated with Cervitec and the lesions in the Placebo group were coated with a Placebo varnish. Treatments were repeated five times in a 12-month period. Clinical parameters associated with root caries, measurements of individual lesions and salivary levels of caries associated bacteria were made at intervals.

RESULTS

The clinical severity of the lesions in the Test group did not change significantly during the 12-month study period. In the Placebo group the mean lesion width and lesion height and length of exposed root increased significantly and the lesions were significantly closer to the gingival margin. There were no significant changes in the salivary levels of caries-associated microorganisms after 12 months although, in both groups, there was initially a significant reduction in the salivary levels of mutans streptococci.

CONCLUSIONS

The combination of Fluor-Protector and Cervitec is a useful, simple, quick and non-invasive method for the control and management of existing root caries lesions. The procedure could be performed by a dental hygienist and may be usefully applied in other high-risk groups including persons with Parkinson's disease, debilitating neuromuscular conditions and dry mouth from whatever cause.

摘要

目的

比较含氟漆(氟保护漆)与含氯己定漆(施卫特)联合使用对一组体弱老年受试者现有根龋损害的临床效果。

方法

采用随机双盲纵向研究。受试者(n = 102)被随机分配到试验组或安慰剂组。所有受试者的所有皮革样和软质根龋损害均涂有氟保护漆,试验组的损害还涂有施卫特,安慰剂组的损害涂有安慰剂漆。在12个月内重复治疗5次。定期进行与根龋相关的临床参数、个体损害测量以及龋相关细菌的唾液水平检测。

结果

在为期12个月的研究期间,试验组损害的临床严重程度无显著变化。在安慰剂组中,平均损害宽度、损害高度以及暴露牙根的长度显著增加,且损害显著更靠近牙龈边缘。12个月后,龋相关微生物的唾液水平无显著变化,不过,两组中变形链球菌的唾液水平最初均有显著降低。

结论

氟保护漆与施卫特联合使用是控制和管理现有根龋损害的一种有用、简单、快速且无创的方法。该操作可由口腔保健员进行,并且可能有效地应用于其他高危人群,包括帕金森病患者、衰弱性神经肌肉疾病患者以及任何原因导致的口干患者。

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