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免疫功能正常的 28 岁男性原发性心脏淋巴瘤的诊断与治疗并发症:病例报告。

Diagnosis and treatment complications of primary cardiac lymphoma in an immunocompetent 28-year old man: a case report.

机构信息

Cardiology Department, Laiko General Hospital, 17 Agiou Thoma Street, 11 527, Athens, Greece.

Heart Failure and Transplant Unit, Onassis Cardiac Surgery Centre, Athens, Greece.

出版信息

BMC Cancer. 2019 Mar 1;19(1):191. doi: 10.1186/s12885-019-5405-y.

Abstract

BACKGROUND

Primary cardiac lymphomas (PCL) represent extremely rare cardiac tumors which are accompanied by poor prognosis, unless they are timely diagnosed and treated.

CASE PRESENTATION

Herein we present a 28-year-old, immunocompetent man who presented to our hospital due to progressively worsening symptoms and signs of superior vena cava syndrome. Multi-modality imaging demonstrated a large intracardiac tumor, which was proven, by biopsy, to be a PCL. The patient received targeted chemotherapy which led to total remission of his disease, with no relapse over a 15-month follow-up period.

CONCLUSIONS

Although PCLs are rare, they should always be kept in mind in the differential diagnosis of cardiac tumors. Timely diagnosis of PCLs and appropriate chemotherapy, alone or in combination with radiotherapy, seems to provide the best results.

摘要

背景

原发性心脏淋巴瘤(PCL)是极为罕见的心脏肿瘤,预后较差,除非及时诊断和治疗。

病例介绍

本病例报告了一位 28 岁免疫功能正常的男性,因上腔静脉综合征的症状和体征逐渐加重而就诊于我院。多模态影像学检查显示心脏内有一个大肿瘤,经活检证实为 PCL。患者接受了靶向化疗,疾病完全缓解,15 个月的随访期内无复发。

结论

尽管 PCL 较为罕见,但在心脏肿瘤的鉴别诊断中应始终考虑到它。及时诊断 PCL 并单独或联合放疗进行适当的化疗,似乎能提供最佳的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cae/6397455/4c6b022ceedd/12885_2019_5405_Fig1_HTML.jpg

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