Marosvölgyi Tamás, Campoy Cristina, Koletzko Berthold, Szabó Eva, Jakobik Viktoria, Jimenez Margarita, Demmelmair Hans, Decsi Tamás
Department of Paediatrics, University of Pécs, Pécs, Hungary.
Adv Exp Med Biol. 2009;646:159-63. doi: 10.1007/978-1-4020-9173-5_18.
Fatty acid composition of erythrocyte phosphatidylcholines was determined by high-resolution capillary gas chromatography in Spanish (n = 120), German (n = 78) and Hungarian (n = 43) expectant women at the 20th week of gestation. The sum of trans isomeric fatty acids was significantly (p < 0.05) lower in Hungarian (0.68 [0.43]% wt/wt, median [IQR]) than in Spanish (0.82 [0.53]) expectant women. There were no significant correlations between the sum of trans isomers and linoleic acid or alpha-linolenic acid in either of the three groups. In contrast, there were significant inverse correlations between the sum of trans fatty acids and arachidonic acid and docosahexaenoic acid in all the three groups. These data raise the possibility that maternal trans isomeric fatty acid status may be inversely associated to the essential fatty acid status of the foetus.
采用高分辨率毛细管气相色谱法测定了西班牙（n = 120）、德国（n = 78）和匈牙利（n = 43）孕20周孕妇红细胞磷脂酰胆碱的脂肪酸组成。匈牙利孕妇反式异构脂肪酸的总量（0.68 [0.43]%重量/重量，中位数[四分位距]）显著低于西班牙孕妇（0.82 [0.53]）（p < 0.05）。三组中反式异构体总量与亚油酸或α-亚麻酸之间均无显著相关性。相反，三组中反式脂肪酸总量与花生四烯酸和二十二碳六烯酸之间均存在显著负相关。这些数据提示，母体反式异构脂肪酸状态可能与胎儿必需脂肪酸状态呈负相关。
