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Hyaluronic acid as a medium for human sperm migration tests.

作者信息

Neuwinger J, Cooper T G, Knuth U A, Nieschlag E

机构信息

Institute of Reproductive Medicine of the University, Münster, FRG.

出版信息

Hum Reprod. 1991 Mar;6(3):396-400. doi: 10.1093/oxfordjournals.humrep.a137348.

DOI:10.1093/oxfordjournals.humrep.a137348
PMID:1955550
Abstract

Hyaluronic acid was used as a substitute for human cervical mucus as a medium for sperm migration since its viscosity, molecular weight and structure are similar to constituent glycoproteins of human cervical mucus. Parameters of sperm motility were comparable in human cervical mucus and hyaluronate as measured by a computerized sperm motion analysis system (Hamilton-Thorn 2030 and Strömberg-Mika System). Sperm migration rates were also similar in human cervical mucus, bovine mucus and hyaluronic acid and the reproducibility was best in hyaluronic acid. Sperm survival for 24 h was maintained in human cervical mucus and hyaluronic acid but not in bovine mucus. The use of hyaluronic acid in sperm migration tests is recommended.

摘要

相似文献

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