尼古丁对体外人精子穿透宫颈黏液能力及运动参数的影响。

Effect of nicotine on in vitro human sperm penetrability through cervical mucus and motility parameters.

作者信息

Crandall L A, Hensleigh H C, Phipps W R

机构信息

Department of Obstetrics and Gynecology, University of Minnesota, Minneapolis.

出版信息

Fertil Steril. 1989 Apr;51(4):722-4. doi: 10.1016/s0015-0282(16)60628-3.

DOI:10.1016/s0015-0282(16)60628-3

PMID:2924941

Abstract

Nicotine at concentrations found in the cervical mucus of female smokers appeared to enhance in vitro human sperm penetrability through ovulatory bovine cervical mucus. Sperm motility parameters were not affected by the addition of nicotine to semen samples incubated with BWW medium. Overall, these results suggest that a direct inhibitory effect of nicotine on sperm penetrability through cervical mucus is not responsible for the apparent increase in cervical factor infertility present in smoking women.

摘要

在女性吸烟者宫颈黏液中发现的尼古丁浓度，似乎能增强体外人精子穿透排卵期牛宫颈黏液的能力。将尼古丁添加到与BWW培养基一起孵育的精液样本中，精子活力参数并未受到影响。总体而言，这些结果表明，尼古丁对精子穿透宫颈黏液的直接抑制作用，并非吸烟女性中明显增加的宫颈因素不孕症的原因。