Pirotta Marie V, Stein Alicia N, Fairley Christopher K, Morrow Andrea, Conway E Lynne, Chuah John, McCloskey Jenny, McNulty Anna, Waddell Russell, Carter Rob, Garland Suzanne
Department of General Practice, University of Melbourne, 200 Berkeley St, Carlton, Victoria 3053, Australia.
Sex Transm Dis. 2009 Jun;36(6):375-9. doi: 10.1097/OLQ.0b013e3181971e4e.
External genital warts are a common sexually transmitted viral disease. We describe the patterns of treatment for initial presentations of external genital warts (EGWs) in Australian sexual health centers.
This was a retrospective audit of 489 case notes from consecutive individuals who presented with a new diagnosis of EGWs to 1 of 5 major sexual health clinics in Australia. Eligibility criteria were consecutive patients aged 18 to 45 years inclusively, presenting with first ever episode of EGWs from January 1, 2004. Exclusion criteria were patients who were immunocompromised, including HIV infection, or enrollment in a treatment study for EGWs.
The median age at presentation of women was 23.2 years and of men 26.8 years. One quarter (n = 127) of patients had another sexually transmitted infection diagnosed at presentation. Nearly half of the patients (n = 224) presented only once for treatment. Most often, patients were treated with a monotherapy (n = 382/489; 78%), usually cryotherapy (257; 53%). Staff applied treatment in 361 (74%) cases. There was wide variation across sites, possibly reflecting local policies and budgets. We found no difference in wart resolution (n = 292; 60%) by initial treatment chosen.
The diagnosis and treatment of genital warts constitute a sizable proportion of clinical visits to the audited sexual health services and require a large input of staff time to manage, including the application of topical treatments. Our results help complete the picture of the burden of EGWs on Australian sexual health centers before the introduction of the HPV vaccine.
外生殖器疣是一种常见的性传播病毒性疾病。我们描述了澳大利亚性健康中心对外生殖器疣(EGW)初发病例的治疗模式。
这是一项对489份病例记录的回顾性审计,这些病例来自澳大利亚5家主要性健康诊所中首次被诊断为EGW的连续患者。纳入标准为年龄在18至45岁(含)之间、自2004年1月1日起首次出现EGW发作的连续患者。排除标准为免疫功能低下的患者,包括HIV感染患者,或参加EGW治疗研究的患者。
就诊时女性的中位年龄为23.2岁,男性为26.8岁。四分之一(n = 127)的患者在就诊时被诊断出患有另一种性传播感染。近一半的患者(n = 224)仅就诊一次接受治疗。大多数情况下,患者接受单一疗法治疗(n = 382/489;78%),通常是冷冻疗法(257例;53%)。工作人员在361例(74%)病例中实施了治疗。各诊所之间存在很大差异,这可能反映了当地政策和预算情况。我们发现,选择的初始治疗方法在疣体消退方面没有差异(n = 292;60%)。
生殖器疣的诊断和治疗在接受审计的性健康服务临床就诊中占相当大的比例,需要大量工作人员时间来管理,包括局部治疗的应用。我们的结果有助于完善在引入HPV疫苗之前EGW对澳大利亚性健康中心造成的负担情况。