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儿童症状性肝囊肿:单次注射盐酸四环素治疗

Symptomatic hepatic cyst in a child: treatment with single-shot injection of tetracycline hydrochloride.

作者信息

Fabrizzi Giancarlo, Lanza Cecilia, Bolli Valeria, Pieroni Giovanni

机构信息

Servizio di Radiologia Generale e Pediatrica, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona 60123, Italy.

出版信息

Pediatr Radiol. 2009 Oct;39(10):1091-4. doi: 10.1007/s00247-009-1323-5. Epub 2009 Jun 26.

Abstract

The prevalence of hepatic cysts is 0.1% to 0.5% based on autopsy studies, and 2.5% based on US examinations. Percutaneous therapies are a new alternative to surgery. They include simple percutaneous aspiration, catheter drainage alone, and catheter drainage with sclerotherapy. We present an 11-year-old boy admitted to hospital because of abdominal pain. A diagnosis of simple hepatic cyst was made, which was treated with aspiration and tetracycline hydrochloride solution (5%) injection into the cystic cavity. Complete regression was seen on US and MRI examination at 3 months, with total collapse and deflation of the cyst. The cyst regressed totally, leaving a hyperechoic linear scar on US examination at 1 year. On the basis of the clinical and imaging results obtained, percutaneous sclerotherapy of hepatic cysts can be recommended as the treatment of choice and as a valid alternative to laparoscopy in children.

摘要

根据尸检研究,肝囊肿的患病率为0.1%至0.5%,而根据超声检查则为2.5%。经皮治疗是手术的一种新替代方法。这些方法包括单纯经皮抽吸、单纯导管引流以及导管引流加硬化治疗。我们报告一名11岁男孩因腹痛入院。诊断为单纯性肝囊肿,采用抽吸并向囊腔内注射5%盐酸四环素溶液进行治疗。3个月时超声和磁共振成像检查显示囊肿完全消退,囊肿完全塌陷并缩小。1年后超声检查发现囊肿完全消退,仅留下一条高回声线性瘢痕。根据所获得的临床和影像学结果,肝囊肿的经皮硬化治疗可推荐作为首选治疗方法,并且是儿童腹腔镜手术的有效替代方法。

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