脑中磷脂酶A2的净活性以及磷脂酶A2-酰化茎的刺激缺乏。
Net activity of phospholipase A2 in brain and the lack of stimulation of the phospholipase A2-acylation stem.
作者信息
Rowe C E
出版信息
Biochem J. 1977 Apr 15;164(1):287-8. doi: 10.1042/bj1640287.
Abstract
Certain observations reported previously from this laboratory have not proved reproducible. These are (1) the relatively rapid hydrolysis of added phosphatidylcholine by phospholipase A2 of tissue from the cerebral cortex of the guinea pig and (2) the stimulation by 10 micron-noradrenaline and by 1.0nM-cyclic AMP of the phospholipase A2-acylation system of isolated synaptic membranes.
摘要
该实验室之前报告的某些观察结果未能得到重复验证。这些观察结果包括：（1）豚鼠大脑皮质组织中的磷脂酶A2对添加的磷脂酰胆碱的相对快速水解，以及（2）10微摩尔去甲肾上腺素和1.0纳摩尔环磷酸腺苷对分离突触膜的磷脂酶A2-酰化系统的刺激作用。
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Net activity of phospholipase A2 in brain and the lack of stimulation of the phospholipase A2-acylation stem.脑中磷脂酶A2的净活性以及磷脂酶A2-酰化茎的刺激缺乏。
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本文引用的文献
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Positional specificites in phospholipid hydrolyses.磷脂水解中的位置特异性
Biochemistry. 1962 Sep;1:804-10. doi: 10.1021/bi00911a012.
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Silica gel stimulates the hydrolysis of lecithin by phospholipase A.
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Statement.声明。
Nature. 1977 Feb 24;265(5596):764. doi: 10.1038/265764b0.
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The stimulation by transmitter substances and putative transmitter substances of the net activity of phospholipase A2 of synaptic membranes of cortex of guinea-pig brain.豚鼠大脑皮层突触膜中磷脂酶A2的净活性受递质物质和假定递质物质的刺激。
Biochem J. 1975 May;148(2):197-208. doi: 10.1042/bj1480197.
7
The effects of noradrenaline, acetylcholine, cyclic AMP, cyclic GMP, and other agents on the concentration of unesterified fatty acids in synaptosomes and synaptic membranes.去甲肾上腺素、乙酰胆碱、环磷酸腺苷、环磷酸鸟苷及其他制剂对突触体和突触膜中游离脂肪酸浓度的影响。
FEBS Lett. 1976 Sep 1;67(3):256-9. doi: 10.1016/0014-5793(76)80541-8.
8
The effects of neurotransmitters and cyclic nucleotides on the metabolism of phospholipids in synaptic membranes of brain.神经递质和环核苷酸对脑突触膜中磷脂代谢的影响。
Adv Exp Med Biol. 1976;72:211-25. doi: 10.1007/978-1-4684-0955-0_18.
9
The stimulation of the phospholipase A2-acylation system of synaptic membranes of brain by cyclic nucleotides.环核苷酸对脑突触膜磷脂酶A2-酰化系统的刺激作用。
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10
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Biochem J. 1975 Jun;148(3):557-65. doi: 10.1042/bj1480557.
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