Konoshima T, Kozuka M
Kyoto Pharmaceutical University, Misasagi, Yamashina-ku 607, Japan.
J Nat Prod. 1991 May-Jun;54(3):830-6. doi: 10.1021/np50075a012.
Two new triterpenoid saponins, wistariasaponins D [1] amd G [2], and the known saponin dehydrosoyasaponin I [3] were isolated from the knots of Wistaria brachybotrys. The Structures of 1 and 2 were determined from their chemical and physicochemical evidence. The inhibitory effects of these saponins on the activation of Epstein-Barr virus early antigen that was induced by a tumor promoter were also tested for the primary screening of antitumor-promoting activities.
从短穗紫藤的节中分离出两种新的三萜皂苷，紫藤皂苷D[1]和G[2]，以及已知的皂苷脱氢大豆皂苷I[3]。根据其化学和物理化学证据确定了1和2的结构。还测试了这些皂苷对由肿瘤启动子诱导的爱泼斯坦-巴尔病毒早期抗原激活的抑制作用，用于抗肿瘤促进活性的初步筛选。
