Adzick N Scott
Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Clin Perinatol. 2009 Jun;36(2):363-76, x. doi: 10.1016/j.clp.2009.03.001.
Prenatal diagnosis provides insight into the in utero evolution of fetal thoracic lesions such as congenital cystic adenomatoid malformation (CCAM), bronchopulmonary sequestration (BPS), congenital lobar emphysema, and mediastinal teratoma. Serial sonographic study of fetuses with thoracic lesions has helped define the natural history of these lesions, determine the pathophysiologic features that affect clinical outcome, and formulate management based on prognosis.
产前诊断有助于深入了解胎儿胸部病变如先天性囊性腺瘤样畸形(CCAM)、肺隔离症(BPS)、先天性大叶性肺气肿和纵隔畸胎瘤在子宫内的演变情况。对患有胸部病变胎儿的系列超声研究有助于明确这些病变的自然病史,确定影响临床结局的病理生理特征,并根据预后制定治疗方案。