National Centre for Natural Products Research (NCNPR), School of Pharmacy, Thad Cochran Research Center, University of Mississippi, MS 38677, USA.
Fitoterapia. 2009 Dec;80(8):496-505. doi: 10.1016/j.fitote.2009.06.012. Epub 2009 Jun 24.
Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional herbal preparations. In this investigation, selected accessions of the plant were examined for diversity through RAPDs, isoenzymes, polypeptide polymorphism and withanolide profiles. The accessions clustered together with respect to their characteristic profile of major withanolides and represented withaferin A, withanone, withanolide D or withanolide A rich groups. This level of phytochemical diversity as discrete chemotypes is widest and is being first ever documented to occur in Indian population of the plant.
睡茄是阿育吠陀医学中最重要的药用植物之一，在印度传统草药制剂中有广泛的应用。在这项研究中，通过 RAPD、同工酶、多肽多态性和醉茄内酯图谱对该植物的选定品系进行了多样性研究。这些品系根据其主要醉茄内酯的特征图谱聚集在一起，代表了含有醉茄亭 A、醉茄酮、醉茄内酯 D 或醉茄内酯 A 的丰富组。这种水平的植物化学多样性作为离散的化学型是最广泛的，并且这是首次在该植物的印度种群中记录到。
