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印度北部军事医院毒蛇咬伤的临床概况

Clinical profile of venomous snake bites in north Indian Military Hospital.

作者信息

Singh Jasjit, Bhoi Sanjeev, Gupta Vineet, Goel Ashish

机构信息

Department of Medicine, Military Hospital, Amritsar.

出版信息

J Emerg Trauma Shock. 2008 Jul;1(2):78-80. doi: 10.4103/0974-2700.43184.

DOI:10.4103/0974-2700.43184
PMID:19561985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2700611/
Abstract

Snakebite is an environmental hazard associated with significant morbidity and mortality. We report a case series of venomous snakebites in a military operational area of north India. Of 33 cases of snake bites presenting to the military hospital, 21 patients were envenomated. The median age of patients was 24 years; all were men. All of the envenomations were neurotoxic in nature. Abdominal pain (91%), headache (86%), dysphagia (86%), ptosis (77%), diplopia (72%), blurred vision (72%), dyspnea (67%), and vomiting (62%) were the predominant clinical presentation. Polyvalent AntiSnakeVenom (ASV) [mean 180 ml; range 90-320 ml] was given to all patients with systemic manifestations, and repeated as needed. Eleven (52%) patients received neostigmine with glycopyrrolate to counter cholinergic effects. Two patients were given ventilatory support. The average time of recovery from envenomation was 16 hours after administration of ASV. All patients recovered without sequelae. Soldiers during military exercise are vulnerable to snakebites. Neurotoxic snakebites predominate in our study and usually present with autonomic features along with headache, abdominal pain, ptosis, diplopia and dysphasia. Preventive measures to minimize snake bites and planned treatment regimens should be emphasized among medical and military personnel deployed in the field operations.

摘要

蛇咬伤是一种与高发病率和死亡率相关的环境危害。我们报告了印度北部一个军事行动地区一系列毒蛇咬伤病例。在前往军事医院就诊的33例蛇咬伤病例中,21例患者发生了中毒。患者的中位年龄为24岁;均为男性。所有中毒均为神经毒性。腹痛(91%)、头痛(86%)、吞咽困难(86%)、上睑下垂(77%)、复视(72%)、视力模糊(72%)、呼吸困难(67%)和呕吐(62%)是主要临床表现。对所有有全身表现的患者均给予了多价抗蛇毒血清(平均180毫升;范围90 - 320毫升),并根据需要重复给药。11例(52%)患者接受了新斯的明与格隆溴铵联合使用以对抗胆碱能效应。2例患者接受了通气支持。中毒后恢复的平均时间为给予抗蛇毒血清后16小时。所有患者均康复且无后遗症。军事演习期间的士兵易被蛇咬伤。在我们的研究中,神经毒性蛇咬伤占主导,通常伴有自主神经症状以及头痛、腹痛、上睑下垂、复视和吞咽困难。在部署于野外行动的医疗和军事人员中,应强调尽量减少蛇咬伤的预防措施和制定好的治疗方案。