从双链支架来源折叠DNA折纸。
Folding DNA origami from a double-stranded source of scaffold.
作者信息
Högberg Björn, Liedl Tim, Shih William M
机构信息
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.
出版信息
J Am Chem Soc. 2009 Jul 8;131(26):9154-5. doi: 10.1021/ja902569x.
Abstract
Combined heat and chemical denaturation of double-stranded DNA scaffold strands in the presence of staple strands, followed by a sudden temperature drop and then stepwise dialysis to remove the chemical denaturant, leads to self-assembly of two distinct DNA-origami structures.
摘要
在存在短链的情况下，对双链DNA支架链进行热和化学联合变性，随后突然降温，然后逐步透析以去除化学变性剂，会导致两种不同的DNA折纸结构自组装。
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