Gillett W R
Department of Obstetrics and Gynaecology, University of Otago, Dunedin, New Zealand.
Reprod Fertil Dev. 1991;3(1):93-8. doi: 10.1071/rd9910093.
To investigate whether the human ovarian surface has an intact epithelial layer, 69 ovarian biopsies from 39 women were taken. When the surface was touched or wiped, there was a widespread loss of cells that were otherwise retained in surface depressions or crypts. By avoiding contact with the surface, the layer was retained. A temporary disruption to the surface following ovulation was followed by complete healing and re-epithelialization. These observations suggest that previous studies describing the loss of surface epithelium may have artifactually generated this loss, possibly by handling the surface during surgical retrieval. The possible clinical significance of these observations is that inadvertent ovarian handling during any ovarian surgery may be implicated in the pathogenesis of adhesion formation, simply by removing the surface that is important in tissue repair.
为研究人类卵巢表面是否有完整的上皮层，取自39名女性的69份卵巢活检样本被采集。当卵巢表面被触碰或擦拭时，原本留存于表面凹陷或隐窝处的细胞出现广泛脱落。若避免与表面接触，该层细胞得以保留。排卵后卵巢表面出现的短暂性破坏会完全愈合并重新上皮化。这些观察结果表明，先前描述表面上皮细胞缺失的研究可能是人为造成了这种缺失，很可能是在手术取材过程中对表面进行了处理。这些观察结果可能具有的临床意义在于，任何卵巢手术中对卵巢的无意操作，可能仅仅通过去除对组织修复很重要的表面，而在粘连形成的发病机制中起作用。
