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快感缺失与吸烟动机之间的关系。

Relations between anhedonia and smoking motivation.

作者信息

Leventhal Adam M, Waters Andrew J, Kahler Christopher W, Ray Lara A, Sussman Steve

机构信息

Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02912, USA.

出版信息

Nicotine Tob Res. 2009 Sep;11(9):1047-54. doi: 10.1093/ntr/ntp098. Epub 2009 Jul 1.

Abstract

INTRODUCTION

A growing literature suggests that anhedonia-an affective dimension related to the inability to experience pleasure-is associated with poor smoking cessation outcomes. Despite these findings, research of the motivational mechanisms linking anhedonia and smoking has been limited. Accordingly, the present study examined (a) relationships between anhedonia and motivationally relevant smoking characteristics and (b) whether anhedonia moderated the effects of tobacco deprivation on appetitive and aversive aspects of smoking urges.

METHODS

Smokers (N = 212; >or=5 cigarettes/day) first attended a baseline session during which measures of anhedonia and smoking characteristics were completed. Prior to a subsequent experimental session, a portion of participants were randomized to one of two groups: (a) 12-hr tobacco deprivation before the session (n = 51) and (b) ad libitum smoking (n = 69).

RESULTS

Smokers with higher levels of anhedonia reported a greater number of past failed quit attempts and a higher proportion of quit attempts that ended in rapid relapse within 24 hr, rs > .20, ps < .05. Anhedonia did not consistently correlate with smoking heaviness, chronicity, and dependence motives. Anhedonia significantly moderated the influence of tobacco deprivation on appetitive smoking urges, such that deprivation effects on appetitive urges were stronger in high anhedonia smokers (beta = .64) than in low anhedonia smokers (beta = .23). Anhedonia did not moderate deprivation effects on aversive smoking urges. This pattern of results remained robust when controlling for baseline negative affect.

DISCUSSION

These findings elucidate anhedonia's link with smoking relapse and could be useful for developing cessation interventions for anhedonic smokers.

摘要

引言

越来越多的文献表明,快感缺失——一种与无法体验愉悦感相关的情感维度——与戒烟效果不佳有关。尽管有这些发现,但关于连接快感缺失与吸烟的动机机制的研究一直很有限。因此,本研究考察了:(a)快感缺失与动机相关的吸烟特征之间的关系,以及(b)快感缺失是否调节了烟草剥夺对吸烟欲望的正向和负向方面的影响。

方法

吸烟者(N = 212;每天吸烟≥5支)首先参加一次基线会话,期间完成快感缺失和吸烟特征的测量。在随后的实验会话之前,一部分参与者被随机分为两组:(a)会话前12小时烟草剥夺组(n = 51)和(b)随意吸烟组(n = 69)。

结果

快感缺失水平较高的吸烟者报告过去戒烟失败的次数更多,且在24小时内迅速复吸的戒烟尝试比例更高,相关系数r>.20,p<.05。快感缺失与吸烟量、吸烟时间和依赖动机之间没有始终如一的相关性。快感缺失显著调节了烟草剥夺对正向吸烟欲望的影响,使得烟草剥夺对高快感缺失吸烟者正向欲望的影响(β = 0.64)强于低快感缺失吸烟者(β = 0.23)。快感缺失没有调节烟草剥夺对负向吸烟欲望的影响。在控制基线消极情绪时,这种结果模式仍然稳健。

讨论

这些发现阐明了快感缺失与吸烟复吸的联系,可能有助于为快感缺失的吸烟者制定戒烟干预措施。

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