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通过腹腔镜灌洗治疗的急性复杂性憩室炎

Acute complicated diverticulitis managed by laparoscopic lavage.

作者信息

Alamili Mahdi, Gögenur Ismail, Rosenberg Jacob

机构信息

Department of Surgery D, Herlev Hospital, Herlev, Denmark.

出版信息

Dis Colon Rectum. 2009 Jul;52(7):1345-9. doi: 10.1007/DCR.0b013e3181a0da34.

Abstract

PURPOSE

The classic surgical treatment of acute complicated sigmoid diverticulitis with peritonitis is often a two-stage operation with colon resection and a temporary stoma. This approach is associated with high mortality and morbidity and the reversal of the stoma is in many cases not performed because of concurrent diseases and age. Recently, several studies have experimented with laparoscopic lavage as a treatment of acute complicated diverticulitis. The aim of this review was to give an overview of the literature for this new approach and to determine the safety compared with Hartmann's procedure for patients with acute complicated sigmoid diverticulitis.

METHODS

A PubMed search was performed for publications between 1990 and May 2008. The terms acute, perforated, diverticulitis, lavage, drainage, and laparoscopy were used in combination. The EMBASE and Cochrane databases were also searched.

RESULTS

Eight studies met the inclusion criteria and reported 213 patients with acute complicated diverticulitis managed by laparoscopic lavage. None of these studies were randomized. The patients' mean age was 59 years and most patients had Hinchey Grade 3 disease. All patients were treated with antibiotics and laparoscopic lavage. Conversion to laparotomy was made in six (3%) patients and the mean hospital stay was nine days. Ten percent of the patients had complications. During the mean follow-up of 38 months, 38% of the patients underwent elective sigmoid resection with primary anastomosis.

CONCLUSION

Primary laparoscopic lavage for complicated diverticulitis may be a promising alternative to more radical surgery in selected patients. Larger studies have to be made before clinical recommendations can be given.

摘要

目的

急性复杂性乙状结肠憩室炎伴腹膜炎的经典外科治疗通常是分两阶段进行的手术,包括结肠切除和临时造口。这种方法与高死亡率和高发病率相关,而且在许多情况下,由于并存疾病和患者年龄因素,造口回纳手术无法实施。最近,有多项研究对腹腔镜灌洗术治疗急性复杂性憩室炎进行了试验。本综述的目的是对这种新方法的文献进行概述,并确定与哈特曼手术相比,其对急性复杂性乙状结肠憩室炎患者的安全性。

方法

在PubMed数据库中检索1990年至2008年5月期间的出版物。检索词组合使用了“急性”“穿孔性”“憩室炎”“灌洗”“引流”和“腹腔镜检查”。同时也检索了EMBASE和Cochrane数据库。

结果

八项研究符合纳入标准,共报告了213例接受腹腔镜灌洗术治疗的急性复杂性憩室炎患者。这些研究均未采用随机对照设计。患者的平均年龄为59岁,大多数患者为欣奇(Hinchey)3级病变。所有患者均接受了抗生素治疗和腹腔镜灌洗术。6例(3%)患者中转开腹手术,平均住院时间为9天。10%的患者出现并发症。在平均38个月的随访期内,38%的患者接受了择期乙状结肠切除术并进行了一期吻合。

结论

对于部分患者,原发性腹腔镜灌洗术治疗复杂性憩室炎可能是一种比更激进手术更有前景的替代方法。在给出临床建议之前,还需要进行更大规模的研究。

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