Vaartjes Ilonca, Hendrix Anneke, Hertogh Emmy M, Grobbee Diederick E, Doevendans Pieter A, Mosterd Arend, Bots Michiel L
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands.
Eur J Cardiovasc Prev Rehabil. 2009 Oct;16(5):592-6. doi: 10.1097/HJR.0b013e32832d555b.
The problem of sudden death in the young is currently debated and measures for prevention are being evaluated worldwide. Information on the incidence and causes of sudden (cardiac) death in the young (1-40 years) is essential for the development of these preventive strategies.
Incidence estimates and causes of death were determined using death certificate data of out-of-hospital sudden deaths recorded by Statistics Netherlands from 1996 to 2006. To define sudden death, International Classification of Diseases codes were selected based on a systematic review of the literature assessing the most common causes of sudden death in the young.
The incidence of sudden death was 2.07 (2.06-2.07 per 100 000 person-years). The incidence was higher for men (2.86 per 100 000 person-years) than for women (1.24 per 100 000 person-years) and increased by age. The majority of sudden deaths was of cardiac origin. Sudden cardiac death incidence was 1.62 (1.61-1.62 per 100 000 person-years). In 9% the cause of death remained unexplained.
The incidence of sudden death in the young is 2.07 per 100 000 person-years. Treatable cardiac causes (such as coronary atherosclerosis and inherited cardiac diseases) are often underlying for the sudden death. This information is helpful in the development of preventive strategies.
年轻人猝死问题目前正在全球范围内展开讨论，预防措施也在评估之中。了解年轻人（1至40岁）猝死（心脏性）的发病率及病因，对于制定这些预防策略至关重要。
利用荷兰统计局1996年至2006年记录的院外猝死死亡证明数据，确定发病率估计值和死因。为定义猝死，基于对评估年轻人猝死最常见病因的文献系统综述，选择了国际疾病分类编码。
猝死发病率为每10万人年2.07例（2.06 - 2.07例）。男性发病率（每10万人年2.86例）高于女性（每10万人年1.24例），且随年龄增长而上升。大多数猝死源于心脏。心源性猝死发病率为每10万人年1.62例（1.61 - 1.62例）。9%的死亡原因不明。
年轻人猝死发病率为每10万人年2.07例。可治疗的心脏病因（如冠状动脉粥样硬化和遗传性心脏病）往往是猝死的潜在原因。这些信息有助于制定预防策略。
