• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes.米糠油饮食可改善链脲佐菌素/烟酰胺诱导的 2 型糖尿病大鼠的脂质异常和抑制高胰岛素血症反应。
J Clin Biochem Nutr. 2009 Jul;45(1):29-36. doi: 10.3164/jcbn.08-257. Epub 2009 Jun 30.
2
A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes.米糠油饮食可增加链脲佐菌素/烟酰胺诱导的2型糖尿病大鼠的低密度脂蛋白受体和HMG-CoA还原酶mRNA表达以及胰岛素敏感性。
J Nutr. 2006 Jun;136(6):1472-6. doi: 10.1093/jn/136.6.1472.
3
Gamma-oryzanol ameliorates insulin resistance and hyperlipidemia in rats with streptozotocin/nicotinamide-induced type 2 diabetes.γ-谷维素可改善链脲佐菌素/烟酰胺诱导的 2 型糖尿病大鼠的胰岛素抵抗和血脂异常。
Int J Vitam Nutr Res. 2010 Jan;80(1):45-53. doi: 10.1024/0300-9831/a000005.
4
Rice bran oil and oryzanol reduce plasma lipid and lipoprotein cholesterol concentrations and aortic cholesterol ester accumulation to a greater extent than ferulic acid in hypercholesterolemic hamsters.在高胆固醇血症仓鼠中，米糠油和谷维素比阿魏酸能更大程度地降低血浆脂质和脂蛋白胆固醇浓度以及主动脉胆固醇酯蓄积。
J Nutr Biochem. 2007 Feb;18(2):105-12. doi: 10.1016/j.jnutbio.2006.03.006. Epub 2006 May 18.
5
Rice Bran Oil Containing Gamma-Oryzanol Improves Lipid Profiles and Antioxidant Status in Hyperlipidemic Subjects: A Randomized Double-Blind Controlled Trial.含γ-谷维素的米糠油改善高脂血症患者的血脂谱和抗氧化状态：一项随机双盲对照试验。
J Altern Complement Med. 2019 Mar;25(3):353-358. doi: 10.1089/acm.2018.0212. Epub 2018 Sep 28.
6
Dietary Wheat Bran Oil Is Equally as Effective as Rice Bran Oil in Reducing Plasma Cholesterol.饮食麦胚油在降低血浆胆固醇方面与米糠油同样有效。
J Agric Food Chem. 2018 Mar 21;66(11):2765-2774. doi: 10.1021/acs.jafc.7b06093. Epub 2018 Mar 9.
7
Rice Bran Oil Improves Insulin Resistance by Affecting the Expression of Antioxidants and Lipid-Regulatory Genes.米糠油通过影响抗氧化剂和脂质调节基因的表达来改善胰岛素抵抗。
Lipids. 2018 May;53(5):505-515. doi: 10.1002/lipd.12045. Epub 2018 Jul 17.
8
Effect of rice bran oil addition on the oxidative degradation and fatty acid composition of soybean oil during heating.添加米糠油对大豆油加热过程中氧化降解及脂肪酸组成的影响。
Acta Sci Pol Technol Aliment. 2019 Oct-Dec;18(4):427-438. doi: 10.17306/J.AFS.0694.
9
Determination of γ-Oryzanol in Refined Rice Bran Oil by Nuclear Magnetic Resonance Method.核磁共振法测定精制米糠油中的γ-谷维素
J Nutr Sci Vitaminol (Tokyo). 2019;65(Supplement):S72-S74. doi: 10.3177/jnsv.65.S72.
10
Feeding unsaponifiable compounds from rice bran oil does not alter hepatic mRNA abundance for cholesterol metabolism-related proteins in hypercholesterolemic rats.给高胆固醇血症大鼠喂食米糠油中的不皂化物不会改变肝脏中胆固醇代谢相关蛋白的mRNA丰度。
Biosci Biotechnol Biochem. 2001 Feb;65(2):371-7. doi: 10.1271/bbb.65.371.

引用本文的文献

1
An open label randomized controlled trial of the effects of rice bran oil on cardiometabolic risk factors, lipid peroxidation and antioxidant status in overweight/obese adults with metabolic syndrome.一项关于米糠油对超重/肥胖代谢综合征成年人的心血管代谢风险因素、脂质过氧化和抗氧化状态影响的开放性随机对照试验。
Lipids Health Dis. 2024 Aug 28;23(1):273. doi: 10.1186/s12944-024-02260-4.
2
An Overview of Herbal-Based Antidiabetic Drug Delivery Systems: Focus on Lipid- and Inorganic-Based Nanoformulations.基于草药的抗糖尿病药物递送系统概述：聚焦于脂质和无机基纳米制剂
Pharmaceutics. 2022 Oct 8;14(10):2135. doi: 10.3390/pharmaceutics14102135.
3
Rice bran oil could favorably ameliorate atherogenicity and insulin resistance indices among men with coronary artery disease: post hoc analysis of a randomized controlled trial.米糠油可改善冠心病男性的动脉粥样硬化和胰岛素抵抗指标：一项随机对照试验的事后分析。
Lipids Health Dis. 2021 Nov 6;20(1):153. doi: 10.1186/s12944-021-01584-9.
4
Influence of germinated brown rice-based flour modified by MAse on type 2 diabetic mice and HepG2 cell cytotoxic capacity.麦芽糊精修饰的发芽糙米粉对2型糖尿病小鼠和HepG2细胞细胞毒性能力的影响。
Food Sci Nutr. 2020 Nov 29;9(2):781-793. doi: 10.1002/fsn3.2043. eCollection 2021 Feb.
5
Modulation of Lipid Transport and Adipose Tissue Deposition by Small Lipophilic Compounds.小分子亲脂性化合物对脂质转运和脂肪组织沉积的调节作用
Front Cell Dev Biol. 2020 Oct 14;8:555359. doi: 10.3389/fcell.2020.555359. eCollection 2020.
6
Actions of annatto-extracted tocotrienol supplementation on obese postmenopausal women: study protocol for a double-blinded, placebo-controlled, randomised trial.姜黄提取物生育三烯酚补充剂对肥胖绝经后妇女的作用：一项双盲、安慰剂对照、随机试验的研究方案。
BMJ Open. 2020 Mar 8;10(3):e034338. doi: 10.1136/bmjopen-2019-034338.
7
Potential Role of Tocotrienols on Non-Communicable Diseases: A Review of Current Evidence.tocotrienols 对非传染性疾病的潜在作用：当前证据综述。
Nutrients. 2020 Jan 19;12(1):259. doi: 10.3390/nu12010259.
8
Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review.米糠来源的生物活性化合物调节心血管疾病和 2 型糖尿病的危险因素：最新综述。
Nutrients. 2019 Nov 12;11(11):2736. doi: 10.3390/nu11112736.
9
The Role of Tocotrienol in Protecting Against Metabolic Diseases.tocotrienol 在预防代谢性疾病中的作用。
Molecules. 2019 Mar 6;24(5):923. doi: 10.3390/molecules24050923.
10
Vitamin E As a Potential Interventional Treatment for Metabolic Syndrome: Evidence from Animal and Human Studies.维生素E作为代谢综合征的一种潜在干预治疗方法：来自动物和人体研究的证据。
Front Pharmacol. 2017 Jul 5;8:444. doi: 10.3389/fphar.2017.00444. eCollection 2017.

本文引用的文献

1
A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes.米糠油饮食可增加链脲佐菌素/烟酰胺诱导的2型糖尿病大鼠的低密度脂蛋白受体和HMG-CoA还原酶mRNA表达以及胰岛素敏感性。
J Nutr. 2006 Jun;136(6):1472-6. doi: 10.1093/jn/136.6.1472.
2
Dietary fatty acids regulate cholesterol induction of liver CYP7alpha1 expression and bile acid production.膳食脂肪酸调节肝脏CYP7α1表达的胆固醇诱导及胆汁酸生成。
Lipids. 2005 May;40(5):455-62. doi: 10.1007/s11745-005-1404-2.
3
Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women.非高密度脂蛋白胆固醇、载脂蛋白A-I和B100、标准血脂指标、血脂比值以及C反应蛋白作为女性心血管疾病的危险因素。
JAMA. 2005 Jul 20;294(3):326-33. doi: 10.1001/jama.294.3.326.
4
Regulation of plasma triglycerides in insulin resistance and diabetes.胰岛素抵抗和糖尿病中血浆甘油三酯的调节
Arch Med Res. 2005 May-Jun;36(3):232-40. doi: 10.1016/j.arcmed.2005.01.005.
5
Lead exposure and (n-3) fatty acid deficiency during rat neonatal development alter liver, plasma, and brain polyunsaturated fatty acid composition.大鼠新生儿发育期间的铅暴露和（n-3）脂肪酸缺乏会改变肝脏、血浆和大脑的多不饱和脂肪酸组成。
J Nutr. 2005 May;135(5):1027-33. doi: 10.1093/jn/135.5.1027.
6
Comparative analysis of the oil and supercritical CO2 extract of Elettaria cardamomum (L.) Maton.小豆蔻（Elettaria cardamomum (L.) Maton.）油脂提取物与超临界二氧化碳提取物的对比分析
J Agric Food Chem. 2004 Oct 6;52(20):6278-82. doi: 10.1021/jf034819i.
7
Similar cholesterol-lowering properties of rice bran oil, with varied gamma-oryzanol, in mildly hypercholesterolemic men.米糠油中γ-谷维素含量不同时，对轻度高胆固醇血症男性的降胆固醇特性相似。
Eur J Nutr. 2005 Mar;44(3):163-73. doi: 10.1007/s00394-004-0508-9. Epub 2004 May 19.
8
A simple method for the isolation and purification of total lipides from animal tissues.一种从动物组织中分离和纯化总脂质的简单方法。
J Biol Chem. 1957 May;226(1):497-509.
9
Quality of dietary fatty acids, insulin sensitivity and type 2 diabetes.膳食脂肪酸质量、胰岛素敏感性与2型糖尿病
Biomed Pharmacother. 2003 Mar;57(2):84-7. doi: 10.1016/s0753-3322(03)00003-9.
10
Cardiovascular disease and diabetes.心血管疾病和糖尿病。
Diabetes Care. 2003 Jan;26(1):230-7. doi: 10.2337/diacare.26.1.230.

米糠油饮食可改善链脲佐菌素/烟酰胺诱导的 2 型糖尿病大鼠的脂质异常和抑制高胰岛素血症反应。

A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes.

机构信息

Department of Tourism and Hospitality Management, Kainan University, Taoyuan 33857, Taiwan.

出版信息

J Clin Biochem Nutr. 2009 Jul;45(1):29-36. doi: 10.3164/jcbn.08-257. Epub 2009 Jun 30.

DOI:10.3164/jcbn.08-257
PMID:19590704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2704324/
Abstract

The aim of this study was to determine the effects of rice bran oil (RBO) on lipid metabolism and insulin resistance in rats with streptozotocin/nicotinamide-induced type 2 diabetes mellitus (T2DM). Rats were divided into two groups: the control group (15% soybean oil, contains 0 g gamma-oryzanol and 0 g gamma-tocotrienol/150 g oil for 5 weeks) and the RBO group (15% RBO, contains 5.25 g gamma-oryzanol and 0.9 g gamma-tocotrienol/150 g oil for 5 weeks). Compared with the control group, the RBO group had a lower plasma nonesterified fatty acid concentration, ratio of total to high-density-lipoprotein cholesterol, hepatic cholesterol concentration, and area under the curve for insulin. The RBO group had a higher high-density-lipoprotein cholesterol concentration and greater excretion of fecal neutral sterols and bile acid than did the control group. RBO may improve lipid abnormalities, reduce the atherogenic index, and suppress the hyperinsulinemic response in rats with streptozotocin/nicotinamide-induced T2DM. In addition, RBO can lead to increased fecal neutral sterol and bile acid excretion.

摘要

本研究旨在探讨米糠油（RBO）对链脲佐菌素/烟酰胺诱导的 2 型糖尿病（T2DM）大鼠脂代谢和胰岛素抵抗的影响。大鼠分为两组：对照组（15%豆油，含 0 gγ-谷维素和 0 gγ-生育三烯酚/150 g 油，5 周）和 RBO 组（15%RBO，含 5.25 gγ-谷维素和 0.9 gγ-生育三烯酚/150 g 油，5 周）。与对照组相比，RBO 组的血浆非酯化脂肪酸浓度、总胆固醇与高密度脂蛋白胆固醇比值、肝胆固醇浓度和胰岛素曲线下面积较低。RBO 组的高密度脂蛋白胆固醇浓度较高，粪便中性固醇和胆汁酸排泄量也大于对照组。RBO 可能改善 T2DM 大鼠的脂代谢异常，降低致动脉粥样硬化指数，抑制高胰岛素血症反应。此外，RBO 可导致粪便中性固醇和胆汁酸排泄增加。