Ribeiro Sérgio Conti, Tormena Renata Assef, Peterson Thais Villela, Gonzáles Marina de Oliveira, Serrano Priscila Gonçalves, Almeida José Alcione Macedo de, Baracat Edmund Chada
Department of Gynecology and Obstetrics, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Sao Paulo Med J. 2009 May;127(2):92-6. doi: 10.1590/s1516-31802009000200007.
The aim of this paper was to discuss the embryological aspects of Müllerian duct anomalies and to analyze the current diagnostic methods and therapy. Müllerian anomalies are congenital defects of the female reproductive tract resulting from failure in the development of the Müllerian ducts and their associated structures. Their cause has yet to be fully clarified, and it is currently believed to be multifactorial. Symptoms appear principally during adolescence or early adulthood, and affect the reproductive capacity of these women. When clinically suspected, investigations leading to diagnosis include imaging methods such as hysterosalpingography, ultrasonography and magnetic resonance. The classification of these malformations relates to their embryogenesis, and defines the therapy and prognosis. Müllerian anomalies consist of a wide range of defects that may vary from patient to patient. Therefore, their management must also be individual, taking anatomical and clinical characteristics into consideration, as well as the patient's wishes.
本文旨在探讨苗勒管异常的胚胎学方面,并分析当前的诊断方法和治疗方法。苗勒管异常是女性生殖道的先天性缺陷,由苗勒管及其相关结构发育失败引起。其病因尚未完全阐明,目前认为是多因素的。症状主要出现在青春期或成年早期,并影响这些女性的生殖能力。临床怀疑时,诊断性检查包括子宫输卵管造影、超声检查和磁共振成像等影像学方法。这些畸形的分类与它们的胚胎发生有关,并决定治疗方法和预后。苗勒管异常包括广泛的缺陷,不同患者之间可能有所不同。因此,其治疗也必须个体化,要考虑解剖和临床特征以及患者的意愿。