甘草酸及其半合成衍生物的抗病毒特性。
Antiviral properties of glycyrrhizic acid and its semisynthetic derivatives.
作者信息
Pompei Raffaello, Laconi Samuela, Ingianni Angela
机构信息
Sezione di Microbiologia, Dept. of STB, University of Cagliari, Via Porcell 4, 09124 Cagliari, Italy.
出版信息
Mini Rev Med Chem. 2009 Jul;9(8):996-1001. doi: 10.2174/138955709788681636.
PMID:19601894
Abstract
Some natural triterpenes exert a definite antiviral activity on several human viruses. New synthetic derivatives of glycyrrhizic acid (GL) are even more active than the parental molecule. GL can alter the expression of viral genes involved in cell transformation, thus opening a new window for speculating on viral cancerogenesis.
摘要
一些天然三萜类化合物对多种人类病毒具有明确的抗病毒活性。甘草酸（GL）的新型合成衍生物甚至比母体分子更具活性。GL可以改变参与细胞转化的病毒基因的表达，从而为推测病毒致癌作用打开了一扇新窗口。
Zotero 插件