Reynolds C P, Pérez-Polo J R
Department of Zoology, University of Texas at Austin, Austin, Tex., U.S.A.
Neurosci Lett. 1975 Aug;1(2):91-7. doi: 10.1016/0304-3940(75)90051-8.
Rat C-6 glioma cells release a factor into culture medium which induces morphological differentiation in the IMR-32 human neuroblastoma cell line. The time course of differentiation and the effects on cell growth differ from those observed in mouse neuroblastoma cells. The effects of other cell lines and the relationship of differentiation to cell growth are discussed.
大鼠C-6胶质瘤细胞向培养基中释放一种因子,该因子可诱导IMR-32人神经母细胞瘤细胞系发生形态分化。分化的时间进程以及对细胞生长的影响与在小鼠神经母细胞瘤细胞中观察到的不同。本文还讨论了其他细胞系的作用以及分化与细胞生长的关系。