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[紫外线照射不足条件下人体紫外线照射后效应的持续时间]

[The duration of the aftereffects of UV-irradiation of man in conditions of UV-insufficiency].

作者信息

Panferova N E, Pervushin V I, Lebedev V I, Belakovskiĭ M S, Khaĭdakov M S, Gutorova L V, Kabasheva T A, Khodkevich Iu N, Rykova M P

出版信息

Kosm Biol Aviakosm Med. 1991 Jul-Aug;25(4):54-6.

PMID:1960957
Abstract

The purpose of the present investigation was to study the aftereffect of UV-B-irradiation applied during 10 or 20 sessions. The biological effect and aftereffect duration of UV-B-irradiation of the upper body of 9 healthy volunteers (residents of the city of Moscow and its suburbs) were evaluated in autumn and winter. During UV-irradiation in the range 220-280, 280-320, or 320-400 nm the flux density was 0.035, 1.75, or 0.65 W/m2, respectively. Group 1 subjects (5 men) were exposed to UV-B-irradiation 10 times (once with 0.5, 0.6, 0.75, 0.9, 1.1, 1.35, 1.65 MED and three times with 2.0 MED) and Group 2 subjects (4 men) were exposed to UV-B-irradiation 20 times (twice with 0.5, 0.75, 1.0, 1.25, 1.5, 1.75 MED and eight times with 2 MED). The sessions were arranged every other day. The exposure produced a beneficial effect on the human body: skin sensitivity decreased, resistance of skin capillaries increased, Ca metabolism normalized, blood 25 (OH) D grew. The trend of responses was similar after 10 and 20 sessions; however, 20 sessions caused a longer-term aftereffect. In relation to space programs, it is concluded that UV-irradiation can be applied on the ground before short-term flights (less than 4 months) and in space during longer-term flights (greater than 4 months).

摘要

本研究的目的是探讨进行10次或20次UV - B照射后的后效应。在秋季和冬季对9名健康志愿者(莫斯科市及其郊区居民)上半身进行UV - B照射,评估其生物学效应和后效应持续时间。在220 - 280、280 - 320或320 - 400 nm的紫外线照射期间,通量密度分别为0.035、1.75或0.65 W/m²。第1组受试者(5名男性)接受10次UV - B照射(一次分别为0.5、0.6、0.75、0.9、1.1、1.35、1.65最小红斑量,三次为2.0最小红斑量),第2组受试者(4名男性)接受20次UV - B照射(两次分别为0.5、0.75、1.0、1.25、1.5、1.75最小红斑量,八次为2最小红斑量)。照射 sessions 每隔一天进行一次。照射对人体产生了有益影响:皮肤敏感性降低,皮肤毛细血管抵抗力增强,钙代谢正常化,血液中25(OH)D增加。10次和20次照射后的反应趋势相似;然而,20次照射产生的后效应持续时间更长。关于太空计划,得出的结论是,紫外线照射可在短期飞行(少于4个月)前在地面进行,在长期飞行(超过4个月)期间在太空中进行。

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Kosm Biol Aviakosm Med. 1991 Jul-Aug;25(4):54-6.
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