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衰老过程中人类大脑皮质和纹状体的形态测量学

Morphometry of the human cortex cerebri and corpus striatum during aging.

作者信息

Haug H, Eggers R

机构信息

Department of Anatomy, Medical University, Germany, West Lübeck.

出版信息

Neurobiol Aging. 1991 Jul-Aug;12(4):336-8; discussion 352-5. doi: 10.1016/0197-4580(91)90013-a.

Abstract

The commentary is based on our results of biological aging research with the following findings: a loss of neurons cannot be found, the size of neurons and the number of synapses decrease with age, the various regions of brain react quite differently. Altogether, these results speak for "use it or lose it." However, the genetically determined decreased brain function during aging can only be inhibited, not permanently preserved.

摘要

这篇评论基于我们生物衰老研究的结果,有以下发现:未发现神经元丢失,神经元大小和突触数量随年龄增长而减少,大脑不同区域的反应差异很大。总体而言,这些结果支持“用进废退”。然而,衰老过程中基因决定的脑功能下降只能被抑制,无法永久保持。

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