Department of Schizophrenia Research, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya, Tokyo, Japan.
Acta Psychiatr Scand. 2010 Apr;121(4):301-7. doi: 10.1111/j.1600-0447.2009.01439.x. Epub 2009 Jul 15.
Psychotic disorders are a significant risk factor for suicide, especially among young people. Psychotic-like experiences (PLEs) in the general population may share an etiological background with psychotic disorders. Therefore, the present study examined the association between PLEs and risk of suicide in a community sample of adolescents.
Psychotic-like experiences, suicidal feelings, and self-harm behaviors were studied using a self-report questionnaire administered to 5073 Japanese adolescents. Depression and anxiety were evaluated using the 12-item General Health Questionnaire (GHQ).
The presence of PLEs was significantly associated with suicidal feelings (OR = 3.1, 95% CI = 2.2-4.5) and deliberate self-harm behaviors (OR = 3.1, 95% CI = 2.0-4.8) after controlling for the effects of age, gender, GHQ-12 score, victimization, and substance use. Suicidal feelings and behaviors were more prevalent in subjects with a greater number of PLEs.
Psychotic-like experiences may increase the risk of suicidal problems among adolescents.
精神障碍是自杀的一个重要危险因素，尤其是在年轻人中。一般人群中的类精神病体验（PLEs）可能与精神病障碍具有共同的病因背景。因此，本研究在青少年的社区样本中研究了 PLEs 与自杀风险之间的关联。
使用自我报告问卷对 5073 名日本青少年进行了类精神病体验、自杀感受和自残行为的研究。使用 12 项一般健康问卷（GHQ）评估抑郁和焦虑。
在控制年龄、性别、GHQ-12 评分、受害和物质使用的影响后，存在 PLEs 与自杀感受（OR=3.1，95%CI=2.2-4.5）和故意自残行为（OR=3.1，95%CI=2.0-4.8）显著相关。有更多 PLEs 的受试者中，自杀感受和行为更为普遍。
类精神病体验可能会增加青少年出现自杀问题的风险。
